(4-(1H-naphtho[1,8-de][1,3,2]diazaborinin-2(3H)-yl)phenyl)methanol

Base Information

• Chemical Name: (4-(1H-naphtho[1,8-de][1,3,2]diazaborinin-2(3H)-yl)phenyl)methanol
• CAS No.: 1072960-84-9
• Molecular Formula: C₁₇H₁₅BN₂O
• Molecular Weight: 274.13
• Mol file: 1072960-84-9.mol

Synonyms:(4-(1H-naphtho[1,8-de][1,3,2]diazaborinin-2(3H)-yl)phenyl)methanol

Chemical Property of (4-(1H-naphtho[1,8-de][1,3,2]diazaborinin-2(3H)-yl)phenyl)methanol

Chemical Property:

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (4-(1H-naphtho[1,8-de][1,3,2]diazaborinin-2(3H)-yl)phenyl)methanol

There total 2 articles about (4-(1H-naphtho[1,8-de][1,3,2]diazaborinin-2(3H)-yl)phenyl)methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

p-hydroxymethylphenylboronic acid (59016-93-2) + naphthalene-1,8-diamine (479-27-6) → (4-(1H-naphtho[1,8-de][1,3,2]diazaborinin-2(3H)-yl)phenyl)methanol (1072960-84-9)

Guidance literature:

In dimethyl sulfoxide; toluene; for 12h; Inert atmosphere;

DOI:10.1021/ja8063759

Reference yield: 80.0%

formaldehyd (50-00-0,30525-89-4,61233-19-0) + 1-(2,3-dihydro-1H-naphtho[1,8-de]-1,3,2-diazaborinyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzene (950511-16-7) → (4-(1H-naphtho[1,8-de][1,3,2]diazaborinin-2(3H)-yl)phenyl)methanol (1072960-84-9)

Guidance literature:

With bis(η3-allyl-μ-chloropalladium(II)); 1-(2-bromophenyl)-3-(2,6-diisopropylphenyl)-4,5-dihydroimidazolinium chloride; In tetrahydrofuran; water; at 100 ℃; for 2h; Inert atmosphere; Sealed tube;

DOI:10.1016/j.tet.2014.11.051

upstream raw materials:

p-hydroxymethylphenylboronic acid

naphthalene-1,8-diamine

formaldehyd

1-(2,3-dihydro-1H-naphtho[1,8-de]-1,3,2-diazaborinyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzene