Technology Process of (SiS)-1-isopropyl-1-[(1R,2S,5R)-1-menthyloxy]-1,2,3,4-tetrahydro-1-silanaphthalene
There total 3 articles about (SiS)-1-isopropyl-1-[(1R,2S,5R)-1-menthyloxy]-1,2,3,4-tetrahydro-1-silanaphthalene which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
(-)-menthol;
With
potassium hydride;
In
tetrahydrofuran;
for 1h;
Heating;
rac-1-chloro-1-isopropyl-(1,2,3,4-tetrahydro)-1-silanaphthalene;
In
tetrahydrofuran;
for 4h;
Heating;
DOI:10.1021/ja067780h
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: Cl2 / CCl4 / 0.07 h / 0 °C
2.1: potassium hydride / tetrahydrofuran / 1 h / Heating
2.2: 33 percent / tetrahydrofuran / 4 h / Heating
With
chlorine; potassium hydride;
In
tetrahydrofuran; tetrachloromethane;
DOI:10.1021/ja067780h
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: magnesium; 1,2-dibromoethane / tetrahydrofuran / 14 h / Heating
1.2: 43 percent / LiAlH4 / tetrahydrofuran / 3 h / Heating
2.1: Cl2 / CCl4 / 0.07 h / 0 °C
3.1: potassium hydride / tetrahydrofuran / 1 h / Heating
3.2: 33 percent / tetrahydrofuran / 4 h / Heating
With
chlorine; potassium hydride; magnesium; ethylene dibromide;
In
tetrahydrofuran; tetrachloromethane;
DOI:10.1021/ja067780h
