Technology Process of 2-Quinolinecarboxaldehyde,5,6,7,8-tetrahydro-8-oxo-(9CI)
There total 5 articles about 2-Quinolinecarboxaldehyde,5,6,7,8-tetrahydro-8-oxo-(9CI) which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
8-benzylidene-2-styryl-5,6,7,8-tetrahydroquinoline;
With
ozone;
In
methanol; dichloromethane;
at -77 ℃;
With
dimethylsulfide;
In
methanol; dichloromethane;
at -77 - 20 ℃;
Further stages.;
DOI:10.1021/ja0273694
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: 98 percent / H2; TFA / 10percent Pd/C / 60 h / 20 °C
2.1: 79 percent / Ac2O / 120 h / 150 - 160 °C
3.1: O3 / CH2Cl2; methanol / -77 °C
3.2: 89 percent / Me2S / CH2Cl2; methanol / -77 - 20 °C
With
hydrogen; acetic anhydride; ozone; trifluoroacetic acid;
10percent Pd/C;
In
methanol; dichloromethane;
DOI:10.1021/ja0273694
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: H2; CF3COOH / 10 percent Pd/C / 20 °C
2.1: Ac2O / 150 - 160 °C
3.1: O3; O2 / CH2Cl2; methanol / -77 °C
3.2: Me2S / CH2Cl2; methanol / -77 - 20 °C
With
hydrogen; oxygen; acetic anhydride; ozone; trifluoroacetic acid;
palladium on activated charcoal;
In
methanol; dichloromethane;
1.1: Catalytic hydrogenation / 2.1: Condensation / 3.1: Oxidation / 3.2: Decomposition;
DOI:10.1002/(SICI)1521-3773(19990903)38:17<2543::AID-ANIE2543>3.0.CO;2-9
