(3aS,5S,6S,6aS)-5-(hydroxymethyl)-2,2-dimethyltetrahydrofuro[3,2-d][1,3]dioxol-6-ol

Base Information

• Chemical Name: (3aS,5S,6S,6aS)-5-(hydroxymethyl)-2,2-dimethyltetrahydrofuro[3,2-d][1,3]dioxol-6-ol
• CAS No.: 172949-42-7
• Molecular Formula: C₈H₁₄O₅
• Molecular Weight: 190.196

Synonyms:(3aS,5S,6S,6aS)-5-(hydroxymethyl)-2,2-dimethyltetrahydrofuro[3,2-d][1,3]dioxol-6-ol

Chemical Property of (3aS,5S,6S,6aS)-5-(hydroxymethyl)-2,2-dimethyltetrahydrofuro[3,2-d][1,3]dioxol-6-ol

Chemical Property:

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (3aS,5S,6S,6aS)-5-(hydroxymethyl)-2,2-dimethyltetrahydrofuro[3,2-d][1,3]dioxol-6-ol

There total 1 articles about (3aS,5S,6S,6aS)-5-(hydroxymethyl)-2,2-dimethyltetrahydrofuro[3,2-d][1,3]dioxol-6-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

5-O-(p-chlorobenzoyl)-1,2-O-isopropylidene-α-L-erythro-pentofuranos-3-ulose (320592-02-7) → (3aS,5S,6S,6aS)-5-(hydroxymethyl)-2,2-dimethyltetrahydrofuro[3,2-d][1,3]dioxol-6-ol (172949-42-7) + 5-O-(p-chlorobenzoyl)-1,2-O-isopropylidene-α-L-ribofuranose (320592-05-0)

Guidance literature:

With sodium tetrahydroborate; In ethanol; ethyl acetate; at 0 ℃; for 1h;

DOI:10.1021/jo000510b

Reference yield: 98.0%

benzoyl chloride (98-88-4) + (3aS,5S,6S,6aS)-5-(hydroxymethyl)-2,2-dimethyltetrahydrofuro[3,2-d][1,3]dioxol-6-ol (172949-42-7) → 1,2-di-O-isopropylidene-3,5-di-O-benzoyl-α-L-ribofuranose (171721-12-3)

Guidance literature:

With pyridine; for 3h; Ambient temperature;

DOI:10.1021/jm960098l

Reference yield: 92.0%

benzyl bromide (100-39-0) + (3aS,5S,6S,6aS)-5-(hydroxymethyl)-2,2-dimethyltetrahydrofuro[3,2-d][1,3]dioxol-6-ol (172949-42-7) → (3aS,5S,6S,6aS)-6-(benzyloxy)-5-(benzyloxymethyl)-2,2-dimethyltetrahydrofuro[3,2-d][1,3]dioxole (320592-10-7)

Guidance literature:

With sodium hydride; In tetrahydrofuran; at 0 - 25 ℃;

DOI:10.1021/jo000510b

upstream raw materials:

5-O-(p-chlorobenzoyl)-1,2-O-isopropylidene-α-L-erythro-pentofuranos-3-ulose

Downstream raw materials:

1,2-di-O-isopropylidene-3,5-di-O-benzoyl-α-L-ribofuranose

(3aS,5S,6S,6aS)-6-(benzyloxy)-5-(benzyloxymethyl)-2,2-dimethyltetrahydrofuro[3,2-d][1,3]dioxole

1,4-anhydro-3,5-di-O-benzyl-2-deoxy-L-erythro-pent-1-enitol

3-fluoro-4-(β-L-glyceropentofuran-3-ulos-1-yl)aniline

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 172949-42-7 (3aS,5S,6S,6aS)-5-(hydroxymethyl)-2,2-dimethyltetrahydrofuro[3,2-d][1,3]dioxol-6-ol

Send

Send

Metric Ton KG G Pound L ML

Send

Send