(3-[2(S)-N-(TERT-BUTOXYCARBONYL)-2-AZETIDINYL-METHOXY]PYRIDIN-2-YL)TRIMETHYLAMMONIUM TRIFLUOROMETHANESULFONATE

Base Information

Chemical Name:(3-[2(S)-N-(TERT-BUTOXYCARBONYL)-2-AZETIDINYL-METHOXY]PYRIDIN-2-YL)TRIMETHYLAMMONIUM TRIFLUOROMETHANESULFONATE
CAS No.:233766-75-1
Molecular Formula:CF₃O₃S*C₁₇H₂₈N₃O₃
Molecular Weight:471.498
Hs Code.:
Mol file:233766-75-1.mol

Synonyms:(3-[2(S)-N-(TERT-BUTOXYCARBONYL)-2-AZETIDINYL-METHOXY]PYRIDIN-2-YL)TRIMETHYLAMMONIUM TRIFLUOROMETHANESULFONATE;2-TMA-A85380;2-TMAAP;2-PYRIDINAMINIUM, 3-[[(2S)-1-[(1,1-DIMETHYLETHOXY)CARBONYL]-2-AZETIDINYL]METHOXY]-N,N,N-TRIMETHYL-, SALT WITH TRIFLUOROMETHANESULFONIC ACID;(3-[2(S)-N-(tert-butoxycarbonyl)-2-azetidinyl-methoxy]pyridin-2-yl)-trimethylammonium Trifluoromethanesulfonate;2-Pyridinaminium, 3-[[(2S)-1-[(1,1-dimethylethoxy)carbonyl]-2-azetidinyl]methoxy]-N,N,N-trimethyl-, salt with trifluoromethanesulfonic acid (1:1);TMA-AP;N-Boc-2-trimethylammonium-A 85380 Triflate

Suppliers and Price of (3-[2(S)-N-(TERT-BUTOXYCARBONYL)-2-AZETIDINYL-METHOXY]PYRIDIN-2-YL)TRIMETHYLAMMONIUM TRIFLUOROMETHANESULFONATE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
N-Boc-2-trimethylammonium-A 85380 triflate
2mg
$ 495.00

TRC
N-Boc-2-trimethylammonium-A85380Triflate
50mg
$ 1540.00

Biosynth Carbosynth
N-Boc-2-trimethylammonium-A 85380 triflate
5 mg
$ 318.00

Biosynth Carbosynth
N-Boc-2-trimethylammonium-A 85380 triflate
2 mg
$ 174.90

Biosynth Carbosynth
N-Boc-2-trimethylammonium-A 85380 triflate
50 mg
$ 1911.00

Biosynth Carbosynth
N-Boc-2-trimethylammonium-A 85380 triflate
25 mg
$ 1051.50

Biosynth Carbosynth
N-Boc-2-trimethylammonium-A 85380 triflate
10 mg
$ 578.20

American Custom Chemicals Corporation
(3-[2(S)-N-(TERT-BUTOXYCARBONYL)-2-AZETIDINYL-METHOXY]PYRIDIN-2-YL)TRIMETHYLAMMONIUM TRIFLUOROMETHANESULFONATE 95.00%
5MG
$ 497.32

AK Scientific
N-Boc-2-trimethylammonium-A85380Triflate
50mg
$ 2629.00

Total 2 raw suppliers

Chemical Property of (3-[2(S)-N-(TERT-BUTOXYCARBONYL)-2-AZETIDINYL-METHOXY]PYRIDIN-2-YL)TRIMETHYLAMMONIUM TRIFLUOROMETHANESULFONATE

Chemical Property:

PSA：117.24000
LogP:3.73660

Purity/Quality:

95% ^*data from raw suppliers

N-Boc-2-trimethylammonium-A 85380 triflate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses An intermediate of 2-[18F]F-A85380, which is the first subtype selective PET-radiotracer to visualize the distribution of α4β 2 nicotinic acetylcholine receptors in human brain in vivo.

Technology Process of (3-[2(S)-N-(TERT-BUTOXYCARBONYL)-2-AZETIDINYL-METHOXY]PYRIDIN-2-YL)TRIMETHYLAMMONIUM TRIFLUOROMETHANESULFONATE

There total 3 articles about (3-[2(S)-N-(TERT-BUTOXYCARBONYL)-2-AZETIDINYL-METHOXY]PYRIDIN-2-YL)TRIMETHYLAMMONIUM TRIFLUOROMETHANESULFONATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

: 333-27-7
methyl trifluoromethanesulfonate

: 233766-73-9
2-(dimethylamino)-3-<2(S)-N-(tert-butoxycarbonyl)-2-azetidinylmethoxy>pyridine

: 233766-75-1
(3-<2(S)-N-(tert-butoxycarbonyl)-2-azetidinylmethoxy>pyridin-2-yl)trimethylammonium trifluoromethanesulfonate

Guidance literature:: In toluene;

Reference yield:

: 161511-85-9
2-(S)-hydroxymethyl-azetidine-1-carboxylic acid tert-butyl ester

: 233766-75-1
(3-<2(S)-N-(tert-butoxycarbonyl)-2-azetidinylmethoxy>pyridin-2-yl)trimethylammonium trifluoromethanesulfonate

Guidance literature:: Multi-step reaction with 2 steps

1: 40 percent / DEAD; PPh₃ / tetrahydrofuran

2: 40 percent / toluene

With triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; toluene; 1: Etherification / 2: Methylation;

Reference yield:

: 233766-72-8
2‐dimethylamino‐3‐hydroxypyridine

: 233766-75-1
(3-<2(S)-N-(tert-butoxycarbonyl)-2-azetidinylmethoxy>pyridin-2-yl)trimethylammonium trifluoromethanesulfonate

Guidance literature:: Multi-step reaction with 2 steps

1: 40 percent / DEAD; PPh₃ / tetrahydrofuran

2: 40 percent / toluene

With triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; toluene; 1: Etherification / 2: Methylation;