4-Oxo-cyclohex-2-ene-1,1,3-tricarboxylic acid di-tert-butyl ester 4-methoxy-benzyl ester

Base Information

• Chemical Name: 4-Oxo-cyclohex-2-ene-1,1,3-tricarboxylic acid di-tert-butyl ester 4-methoxy-benzyl ester
• CAS No.: 1026660-25-2
• Molecular Formula: C₂₅H₃₂O₈
• Molecular Weight: 460.524
• Mol file: 1026660-25-2.mol

Synonyms:4-Oxo-cyclohex-2-ene-1,1,3-tricarboxylic acid di-tert-butyl ester 4-methoxy-benzyl ester

Chemical Property of 4-Oxo-cyclohex-2-ene-1,1,3-tricarboxylic acid di-tert-butyl ester 4-methoxy-benzyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-Oxo-cyclohex-2-ene-1,1,3-tricarboxylic acid di-tert-butyl ester 4-methoxy-benzyl ester

There total 4 articles about 4-Oxo-cyclohex-2-ene-1,1,3-tricarboxylic acid di-tert-butyl ester 4-methoxy-benzyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.0%

4-Oxo-3-phenylselanyl-cyclohexane-1,1,3-tricarboxylic acid di-tert-butyl ester 4-methoxy-benzyl ester (180588-00-5) → 4-Oxo-cyclohex-2-ene-1,1,3-tricarboxylic acid di-tert-butyl ester 4-methoxy-benzyl ester (1026660-25-2)

Guidance literature:

With dihydrogen peroxide; In dichloromethane; water; for 0.25h;

DOI:10.1021/jo960245n

Reference yield:

4-methoxybenzyl acrylate (133208-88-5) → 4-Oxo-cyclohex-2-ene-1,1,3-tricarboxylic acid di-tert-butyl ester 4-methoxy-benzyl ester (1026660-25-2)

Guidance literature:

Multi-step reaction with 3 steps

1: 1.) sodium hydride / 1.) THF, 2.) THF, 40 min

2: 1.) pyridine / 1.) CH₂Cl₂, 15 min, 2.) CH₂Cl₂, 0 deg C, 1 h

3: 51 percent / hydrogen peroxide / CH₂Cl₂; H₂O / 0.25 h

With pyridine; dihydrogen peroxide; sodium hydride; In dichloromethane; water;

DOI:10.1021/jo960245n

Reference yield:

4-Methoxybenzyl alcohol (105-13-5) → 4-Oxo-cyclohex-2-ene-1,1,3-tricarboxylic acid di-tert-butyl ester 4-methoxy-benzyl ester (1026660-25-2)

Guidance literature:

Multi-step reaction with 4 steps

1: 1.) sodium hydride / 1.) THF, 40-48 deg C, 15 min, 2.) THF, -78 deg C, 2 h

2: 1.) sodium hydride / 1.) THF, 2.) THF, 40 min

3: 1.) pyridine / 1.) CH₂Cl₂, 15 min, 2.) CH₂Cl₂, 0 deg C, 1 h

4: 51 percent / hydrogen peroxide / CH₂Cl₂; H₂O / 0.25 h

With pyridine; dihydrogen peroxide; sodium hydride; In dichloromethane; water;

DOI:10.1021/jo960245n

upstream raw materials:

4-Oxo-3-phenylselanyl-cyclohexane-1,1,3-tricarboxylic acid di-tert-butyl ester 4-methoxy-benzyl ester

4-methoxybenzyl acrylate

4-Methoxybenzyl alcohol

4-Oxo-cyclohexane-1,1,3-tricarboxylic acid di-tert-butyl ester 4-methoxy-benzyl ester