2-(3-nitrophenyl)acetyl Chloride

Base Information Edit

Chemical Name:2-(3-nitrophenyl)acetyl Chloride
CAS No.:38411-41-5
Molecular Formula:C₈H₆ClNO₃
Molecular Weight:199.594
Hs Code.:
DSSTox Substance ID:DTXSID301307030
Mol file:38411-41-5.mol

Synonyms:2-(3-nitrophenyl)acetyl Chloride;38411-41-5;Benzeneacetyl chloride, 3-nitro-;(3-Nitro-phenyl)-acetyl chloride;3-Nitrobenzeneacetyl chloride;SCHEMBL641742;SCHEMBL14551073;DTXSID301307030;2-(3-nitrophenyl) acetyl chloride;MFCD11053341;AKOS006308665;SY324865;F86819

Suppliers and Price of 2-(3-nitrophenyl)acetyl Chloride

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-(3-nitrophenyl)acetyl Chloride Edit

Chemical Property:

XLogP3:2.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:199.0036207
Heavy Atom Count:13
Complexity:214

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC(=CC(=C1)[N+](=O)[O-])CC(=O)Cl

Technology Process of 2-(3-nitrophenyl)acetyl Chloride

There total 9 articles about 2-(3-nitrophenyl)acetyl Chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.9%

: 1877-73-2
3-nitro-benzeneacetic acid

: 38411-41-5
(3-nitrophenyl)acetyl chloride

Guidance literature:: With thionyl chloride; In N,N-dimethyl-formamide; toluene; at 80 ℃; for 2h;

Reference yield:

: 621-50-1
(3-nitrophenyl)acetonitrile

: 38411-41-5
(3-nitrophenyl)acetyl chloride

Guidance literature:: Multi-step reaction with 2 steps

1: AcOH; H₂SO₄

2: thionyl chloride

With thionyl chloride; sulfuric acid; acetic acid;
DOI:10.3797/scipharm.aut-01-204

Reference yield:

: 7023-81-6
2-diazo-1-(3-nitrophenyl)ethanone

: 38411-41-5
(3-nitrophenyl)acetyl chloride

Guidance literature:: Multi-step reaction with 2 steps

1: aq. Ag₂O / dioxane

2: (COCl)2; DMF / CH₂Cl₂

With oxalyl dichloride; N,N-dimethyl-formamide; silver(l) oxide; In 1,4-dioxane; dichloromethane; 1: Rearrangement / 2: Chlorination;
DOI:10.1016/S0960-894X(00)00318-8