Technology Process of N3-(3-chloro-4-phenoxyphenyl)-1H-[1,2,4]triazole-3,5-diamine
There total 6 articles about N3-(3-chloro-4-phenoxyphenyl)-1H-[1,2,4]triazole-3,5-diamine which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
hydrazine;
In
ethanol;
at 65 ℃;
for 0.5h;
Inert atmosphere;
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: iron; ammonium chloride / water; methanol / 6 h / Reflux
2.1: dichloromethane / 1 h / 0 - 20 °C / Inert atmosphere; Cooling with ice
3.1: sodium methylate / methanol / 0.25 h / Inert atmosphere
3.2: 1 h / 20 °C / Inert atmosphere
3.3: 21 h / 20 °C / Inert atmosphere
4.1: hydrazine / ethanol / 0.5 h / 65 °C / Inert atmosphere
With
sodium methylate; iron; ammonium chloride; hydrazine;
In
methanol; ethanol; dichloromethane; water;
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: potassium carbonate / N,N-dimethyl-formamide / 100 °C
2.1: iron; ammonium chloride / water; methanol / 6 h / Reflux
3.1: dichloromethane / 1 h / 0 - 20 °C / Inert atmosphere; Cooling with ice
4.1: sodium methylate / methanol / 0.25 h / Inert atmosphere
4.2: 1 h / 20 °C / Inert atmosphere
4.3: 21 h / 20 °C / Inert atmosphere
5.1: hydrazine / ethanol / 0.5 h / 65 °C / Inert atmosphere
With
sodium methylate; iron; potassium carbonate; ammonium chloride; hydrazine;
In
methanol; ethanol; dichloromethane; water; N,N-dimethyl-formamide;