Acetic acid 4-[6-(1-methoxy-1-methyl-ethyl)-benzo[1,3]dioxol-5-ylmethyl]-phenyl ester

Base Information

Chemical Name:Acetic acid 4-[6-(1-methoxy-1-methyl-ethyl)-benzo[1,3]dioxol-5-ylmethyl]-phenyl ester
CAS No.:148517-75-3
Molecular Formula:C₂₀H₂₂O₅
Molecular Weight:342.392
Hs Code.:

Synonyms:Acetic acid 4-[6-(1-methoxy-1-methyl-ethyl)-benzo[1,3]dioxol-5-ylmethyl]-phenyl ester

Suppliers and Price of Acetic acid 4-[6-(1-methoxy-1-methyl-ethyl)-benzo[1,3]dioxol-5-ylmethyl]-phenyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Acetic acid 4-[6-(1-methoxy-1-methyl-ethyl)-benzo[1,3]dioxol-5-ylmethyl]-phenyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Acetic acid 4-[6-(1-methoxy-1-methyl-ethyl)-benzo[1,3]dioxol-5-ylmethyl]-phenyl ester

There total 9 articles about Acetic acid 4-[6-(1-methoxy-1-methyl-ethyl)-benzo[1,3]dioxol-5-ylmethyl]-phenyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 108-24-7
acetic anhydride

: 148517-62-8
4'-hydroxy-2-(1-methoxy-1-methylethyl)-4,5-(methylenedioxy)diphenylmethane

: 148517-75-3
Acetic acid 4-[6-(1-methoxy-1-methyl-ethyl)-benzo[1,3]dioxol-5-ylmethyl]-phenyl ester

Guidance literature:: With dmap; In dichloromethane; for 0.166667h;
DOI:10.1021/jo00064a017

Reference yield:

6-bromopiperonylic acid: 60546-62-5
6-bromopiperonylic acid

: 148517-75-3
Acetic acid 4-[6-(1-methoxy-1-methyl-ethyl)-benzo[1,3]dioxol-5-ylmethyl]-phenyl ester

Guidance literature:: Multi-step reaction with 6 steps

1: 95 percent / H₂SO₄ / methanol / 72 h / Heating

2: 80 percent / diethyl ether / 9 °C

3: 1) NaH / 1) THF, RT, 5.0 h, 2) THF, RT, overnight

4: 1) n-BuLi / 1) THF, -78 deg C, 1.75 h, 2)THF, -78 deg C, overnight

5: 70 percent / KF, NaBH₄, 18-crown-6 / acetonitrile / 120 h / Heating

6: 100 percent / DMAP / CH₂Cl₂ / 0.17 h

With dmap; potassium fluoride; sodium tetrahydroborate; n-butyllithium; 18-crown-6 ether; sulfuric acid; sodium hydride; In methanol; diethyl ether; dichloromethane; acetonitrile;
DOI:10.1021/jo00064a017

Reference yield:

: 61441-09-6
methyl 6-bromo-1,3-benzodioxole-5-carboxylate

: 148517-75-3
Acetic acid 4-[6-(1-methoxy-1-methyl-ethyl)-benzo[1,3]dioxol-5-ylmethyl]-phenyl ester

Guidance literature:: Multi-step reaction with 5 steps

1: 80 percent / diethyl ether / 9 °C

2: 1) NaH / 1) THF, RT, 5.0 h, 2) THF, RT, overnight

3: 1) n-BuLi / 1) THF, -78 deg C, 1.75 h, 2)THF, -78 deg C, overnight

4: 70 percent / KF, NaBH₄, 18-crown-6 / acetonitrile / 120 h / Heating

5: 100 percent / DMAP / CH₂Cl₂ / 0.17 h

With dmap; potassium fluoride; sodium tetrahydroborate; n-butyllithium; 18-crown-6 ether; sodium hydride; In diethyl ether; dichloromethane; acetonitrile;
DOI:10.1021/jo00064a017