61441-09-6

Basic information

• Product Name: methyl 6-bromobenzo[d][1,3]dioxole-5-carboxylate
• Synonyms: methyl 6-bromobenzo[d][1,3]dioxole-5-carboxylate
• CAS NO: 61441-09-6
• Molecular Formula: C₉H₇BrO₄
• Molecular Weight: 259.05348
• Mol File: 61441-09-6.mol
• Article Data: 13

Chemical Properties

• Melting Point: 54 °C
• Boiling Point: 316.6°Cat760mmHg
• Flash Point: 145.3°C
• Appearance: /
• Density: 1.674g/cm³
• Vapor Pressure: 0.000406mmHg at 25°C
• Refractive Index: 1.585
• CAS DataBase Reference: methyl 6-bromobenzo[d][1,3]dioxole-5-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 6-bromobenzo[d][1,3]dioxole-5-carboxylate(61441-09-6)
• EPA Substance Registry System: methyl 6-bromobenzo[d][1,3]dioxole-5-carboxylate(61441-09-6)

Safety Data

• Hazardous Substances Data: 61441-09-6(Hazardous Substances Data)

Usage

General Description

Methyl 6-bromobenzo[d][1,3]dioxole-5-carboxylate is a chemical compound with the molecular formula C9H7BrO4. It is a brominated ester derivative of benzo[d][1,3]dioxole, which is commonly used in the synthesis of pharmaceuticals and agrochemicals. methyl 6-bromobenzo[d][1,3]dioxole-5-carboxylate is often employed as a building block in organic synthesis, particularly in the production of biologically active compounds. It is important to handle this chemical with care, as it is potentially hazardous and should only be used in a controlled laboratory setting by trained professionals.

InChI:InChI=1/C9H7BrO4/c1-12-9(11)5-2-7-8(3-6(5)10)14-4-13-7/h2-3H,4H2,1H3

Upstream product

• 7112-80-3 4-amino-benzo[1,3]dioxole-5-carboxylic acid methyl ester 
• 67-56-1 methanol 
• 60546-62-5 6-bromopiperonylic acid 
• 15930-53-7 6-bromo-3,4-methylenedioxybenzaldehyde 
• 94-53-1 Piperonylic acid 
• 74-88-4 methyl iodide 
• 420-37-1 trimethoxonium tetrafluoroborate 
• 148160-25-2 (6-bromo(2H-benzo[3,4-d]1,3-dioxolen-5-yl))-N,N-diethylcarboxamide 
• 149-73-5 trimethyl orthoformate 

Downstream Products

• 2436-96-6 1-nitro-2-(2-nitrophenyl)benzene 
• 40141-86-4 [1,3]dioxolo[4,5-j]-6(5H)-phenanthridinone 
• 40141-98-8 N-methylcrinasiadine 
• 1413256-21-9 N-phenylethylcrinasiadine 
• 52886-06-3 hippadine 
• 2030-55-9 (-)-zephyranthine 
• 6871-57-4 (-)-α-lycorane 
• 40360-71-2 anhydrolycorine-7-one 
• 1187950-50-0 2-methoxy-5-methyl-7H-[1,3]dioxolo[4,5-j]pyrrolo[3,2,1-de]phenanthridin-7-one 
• 906563-77-7 methyl 6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzo[d][1,3]dioxole-5-carboxylate 

Relevant articles and documents

Total Synthesis of Zephycarinatines via Photocatalytic Reductive Radical ipso-Cyclization

We report herein a nonbiomimetic strategy for the total synthesis of the plicamine-type alkaloids zephycarinatines C and D. The key feature of the synthesis is a stereoselective reductive radical ipso-cyclization using visible-light-mediated photoredox ca

Pd-Catalyzed/Iodide-Promoted α-Arylation of Ketones for the Regioselective Synthesis of Isocoumarins

A variety of isocoumarins have been synthesized directly from 2-halobenzoates and ketones through a palladium-catalyzed α-arylation step followed by an intramolecular cyclization process. The addition of iodide anions to the reaction mixture increased yields and selectivities especially when 2-bromobenzoates were employed. This phosphine-free one-pot synthesis features a high functional group tolerance and gives access to richly decorated isocoumarins. This general methodology was successful in the total synthesis of Xyridin A, an important natural product with antibacterial and antifungal activity.

AD-35 preparation technology

The invention discloses a new preparation method of a benzodioxole derivative (AD-35) shown by the formula (I). The method comprises the following steps: with piperic acid as a raw material, performing bromination, esterification, cyaniding, cyclopropane