3-(2-tert-butoxycarbonylethoxy)propionic acid tert-butyl ester

Base Information

• Chemical Name: 3-(2-tert-butoxycarbonylethoxy)propionic acid tert-butyl ester
• CAS No.: 1427320-41-9
• Molecular Formula: C₁₄H₂₆O₅
• Molecular Weight: 274.357
• Mol file: 1427320-41-9.mol

Synonyms:3-(2-tert-butoxycarbonylethoxy)propionic acid tert-butyl ester

Chemical Property of 3-(2-tert-butoxycarbonylethoxy)propionic acid tert-butyl ester

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-(2-tert-butoxycarbonylethoxy)propionic acid tert-butyl ester

There total 1 articles about 3-(2-tert-butoxycarbonylethoxy)propionic acid tert-butyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 56.0%

Pentaerythritol (115-77-5) + tert-Butyl acrylate (1663-39-4,25232-27-3) → di-tert-butyl 3,3'-{[2,2-bis(hydroxymethyl)propane-1,3-diyl]bis(oxy)}dipropanoate (1427320-40-8) + 3-(2-tert-butoxycarbonylethoxy)propionic acid tert-butyl ester (1427320-41-9) + tert-butyl 3-[3-(3-tert-butoxy-3-oxopropoxy)-2-[(3-tert-butoxy-3-oxopropoxy)methyl]-2-(hydroxymethyl)propoxy]propanoate (1027581-61-8) + 3-[3-(2-tert-butoxycarbonylethoxy)-2,2-bis-(2-tert-butoxycarbonylethoxymethyl)propoxy]propionic acid tert-butyl ester (175724-29-5)

Guidance literature:

Pentaerythritol; With sodium hydroxide; In water; at 20 ℃; for 1h; Inert atmosphere; Darkness;

tert-Butyl acrylate; With N-benzyl-N,N,N-triethylammonium chloride; In water; at 20 ℃; for 18h; Reagent/catalyst; Concentration; Inert atmosphere; Darkness; Cooling with ice;

DOI:10.1016/j.molstruc.2013.01.034

Reference yield: 90.0%

3-(2-tert-butoxycarbonylethoxy)propionic acid tert-butyl ester (1427320-41-9) → 3-(2-carboxyethoxy)propionic acid (5961-83-1)

Guidance literature:

With trifluoroacetic acid; at 20 ℃; for 1h;

DOI:10.1016/j.molstruc.2013.01.034

upstream raw materials:

Pentaerythritol

tert-Butyl acrylate

Downstream raw materials:

3-(2-carboxyethoxy)propionic acid