.beta.-D-Galactopyranose, 1,6-anhydro-2-O-(1,1-dimethylethyl)dimethylsilyl-3,4-O-(4-methoxyphenyl)methylene-

Base Information

• Chemical Name: .beta.-D-Galactopyranose, 1,6-anhydro-2-O-(1,1-dimethylethyl)dimethylsilyl-3,4-O-(4-methoxyphenyl)methylene-
• CAS No.: 228115-62-6
• Molecular Formula: C20H30 O6 Si
• Molecular Weight: 394.54
• Mol file: 228115-62-6.mol

Synonyms:.beta.-D-Galactopyranose, 1,6-anhydro-2-O-(1,1-dimethylethyl)dimethylsilyl-3,4-O-(4-methoxyphenyl)methylene-

Chemical Property of .beta.-D-Galactopyranose, 1,6-anhydro-2-O-(1,1-dimethylethyl)dimethylsilyl-3,4-O-(4-methoxyphenyl)methylene-

Chemical Property:

• PSA: 55.38000
• LogP: 3.62330

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of .beta.-D-Galactopyranose, 1,6-anhydro-2-O-(1,1-dimethylethyl)dimethylsilyl-3,4-O-(4-methoxyphenyl)methylene-

There total 1 articles about .beta.-D-Galactopyranose, 1,6-anhydro-2-O-(1,1-dimethylethyl)dimethylsilyl-3,4-O-(4-methoxyphenyl)methylene- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

tert-butyldimethylsilyl chloride (18162-48-6) + (1R,2S,6R,7R,8R)-4-(4-Methoxy-phenyl)-3,5,9,11-tetraoxa-tricyclo[6.2.1.02,6]undecan-7-ol (228115-59-1) → 1,6-anhydro-2-O-tert-butyldimethylsilyl-endo-3,4-O-p-methoxybenzylidene-β-D-galactopyranose (228115-62-6)

Guidance literature:

With 1H-imidazole; In N,N-dimethyl-formamide;

DOI:10.1016/S0040-4020(99)00327-0

Reference yield: 56.0%

1,6-anhydro-2-O-tert-butyldimethylsilyl-endo-3,4-O-p-methoxybenzylidene-β-D-galactopyranose (228115-62-6) → 1,6-anhydro-2-O-tert-butyldimethylsilyl-3-O-p-methoxybenzyl-β-D-galactopyranose (228115-71-7)

Guidance literature:

With lithium aluminium tetrahydride; aluminium trichloride; In tetrahydrofuran; for 2h; Heating;

DOI:10.1016/S0040-4020(99)00327-0

Reference yield:

1,6-anhydro-2-O-tert-butyldimethylsilyl-endo-3,4-O-p-methoxybenzylidene-β-D-galactopyranose (228115-62-6) → 4-O-acetyl-1,6-anhydro-2-O-tert-butyldimethylsilyl-3-O-p-methoxybenzyl-β-D-galactopyranose (228115-73-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 56 percent / lithium aluminum hydride; aluminum chloride / tetrahydrofuran / 2 h / Heating

2: 92 percent / pyridine / 2 h / Heating

With pyridine; lithium aluminium tetrahydride; aluminium trichloride; In tetrahydrofuran; 1: Reduction / 2: Acetylation;

DOI:10.1016/S0040-4020(99)00327-0

upstream raw materials:

tert-butyldimethylsilyl chloride

(1R,2S,6R,7R,8R)-4-(4-Methoxy-phenyl)-3,5,9,11-tetraoxa-tricyclo[6.2.1.0^2,6]undecan-7-ol

Downstream raw materials:

1,6-anhydro-2-O-tert-butyldimethylsilyl-3-O-p-methoxybenzyl-β-D-galactopyranose

4-O-acetyl-1,6-anhydro-2-O-tert-butyldimethylsilyl-β-D-galactopyranose

4-O-acetyl-1,6-anhydro-2-O-tert-butyldimethylsilyl-3-O-p-methoxybenzyl-β-D-galactopyranose