tetrahydro-4-isopropyl-2-<3-(trifluoromethyl)phenyl>-2H-1,4-oxazin-2-ol

Base Information

Chemical Name:tetrahydro-4-isopropyl-2-<3-(trifluoromethyl)phenyl>-2H-1,4-oxazin-2-ol
CAS No.:75247-59-5
Molecular Formula:C₁₄H₁₈F₃NO₂
Molecular Weight:289.298
Hs Code.:

Synonyms:tetrahydro-4-isopropyl-2-<3-(trifluoromethyl)phenyl>-2H-1,4-oxazin-2-ol

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Chemical Property of tetrahydro-4-isopropyl-2-<3-(trifluoromethyl)phenyl>-2H-1,4-oxazin-2-ol

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Technology Process of tetrahydro-4-isopropyl-2-<3-(trifluoromethyl)phenyl>-2H-1,4-oxazin-2-ol

There total 2 articles about tetrahydro-4-isopropyl-2-<3-(trifluoromethyl)phenyl>-2H-1,4-oxazin-2-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.1%

: 109-56-8
i-propyl(2-(hydroxy)ethyl)amine

: 2003-10-3
2-bromo-1-[3-(trifluoromethyl)phenyl]ethanone

: 75247-59-5
tetrahydro-4-isopropyl-2-<3-(trifluoromethyl)phenyl>-2H-1,4-oxazin-2-ol

Guidance literature:: In toluene; for 24h; Ambient temperature;
DOI:10.1021/jo01312a037

Reference yield:

: 349-76-8
3'-(trifluoromethyl)acetophenone

: 75247-59-5
tetrahydro-4-isopropyl-2-<3-(trifluoromethyl)phenyl>-2H-1,4-oxazin-2-ol

Guidance literature:: Multi-step reaction with 2 steps

1: 92.9 percent / Br₂ / CHCl₃ / 1.5 h / Ambient temperature

2: 65.1 percent / toluene / 24 h / Ambient temperature

With bromine; In chloroform; toluene;
DOI:10.1021/jo01312a037