ethyl 1-(4-chlorophenyl)-4-(4-chlorophenylamino)-2,6-bis(phenyl)-1,2,5,6-tetrahydropyridine-3-carboxylate

Base Information

• Chemical Name: ethyl 1-(4-chlorophenyl)-4-(4-chlorophenylamino)-2,6-bis(phenyl)-1,2,5,6-tetrahydropyridine-3-carboxylate
• CAS No.: 74979-96-7
• Molecular Formula: C₃₂H₂₈Cl₂N₂O₂
• Molecular Weight: 543.493
• Mol file: 74979-96-7.mol

Synonyms:ethyl 1-(4-chlorophenyl)-4-(4-chlorophenylamino)-2,6-bis(phenyl)-1,2,5,6-tetrahydropyridine-3-carboxylate

Chemical Property of ethyl 1-(4-chlorophenyl)-4-(4-chlorophenylamino)-2,6-bis(phenyl)-1,2,5,6-tetrahydropyridine-3-carboxylate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of ethyl 1-(4-chlorophenyl)-4-(4-chlorophenylamino)-2,6-bis(phenyl)-1,2,5,6-tetrahydropyridine-3-carboxylate

There total 3 articles about ethyl 1-(4-chlorophenyl)-4-(4-chlorophenylamino)-2,6-bis(phenyl)-1,2,5,6-tetrahydropyridine-3-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

ethyl acetoacetate (141-97-9) + benzaldehyde (100-52-7) + 4-chloro-aniline (106-47-8) → ethyl 1-(4-chlorophenyl)-4-(4-chlorophenylamino)-2,6-bis(phenyl)-1,2,5,6-tetrahydropyridine-3-carboxylate (74979-96-7)

Guidance literature:

With bismuth(III) immobilized on triazine dendrimer stabilized magnetic nanoparticle; In ethanol; at 20 ℃; for 1h; Catalytic behavior;

DOI:10.1021/acscombsci.6b00180

Reference yield: 5.5%

ethyl acetoacetate (141-97-9) + (Z)-3-(4-chloro-phenylamino)-but-2-enoic acid ethyl ester (66558-25-6) + benzaldehyde (100-52-7) → ethyl 1-(4-chlorophenyl)-4-(4-chlorophenylamino)-2,6-bis(phenyl)-1,2,5,6-tetrahydropyridine-3-carboxylate (74979-96-7)

Guidance literature:

In ethanol; for 8h; Heating;

DOI:10.1007/BF00552778

Reference yield: 5.0%

ethyl acetoacetate (141-97-9) + benzaldehyde (100-52-7) + 4-chloro-aniline (106-47-8) → 6-[(E)-4-Chloro-phenylimino]-4-hydroxy-4-methyl-2-phenyl-cyclohexane-1,3-dicarboxylic acid diethyl ester (74979-92-3) + ethyl 1-(4-chlorophenyl)-4-(4-chlorophenylamino)-2,6-bis(phenyl)-1,2,5,6-tetrahydropyridine-3-carboxylate (74979-96-7)

Guidance literature:

In methanol; for 7h; Heating;

DOI:10.1007/BF00552778

upstream raw materials:

ethyl acetoacetate

(Z)-3-(4-chloro-phenylamino)-but-2-enoic acid ethyl ester

benzaldehyde

4-chloro-aniline

Downstream raw materials:

1-(4-Chloro-phenyl)-4-oxo-2,6-diphenyl-piperidine-3-carboxylic acid ethyl ester