(R,R)-(2-ethoxycarbonylaminocyclohexyl)carbamic acid ethyl ester

Base Information

• Chemical Name: (R,R)-(2-ethoxycarbonylaminocyclohexyl)carbamic acid ethyl ester
• CAS No.: 75730-13-1
• Molecular Formula: C₁₂H₂₂N₂O₄
• Molecular Weight: 258.318
• Mol file: 75730-13-1.mol

Synonyms:(R,R)-(2-ethoxycarbonylaminocyclohexyl)carbamic acid ethyl ester

Chemical Property of (R,R)-(2-ethoxycarbonylaminocyclohexyl)carbamic acid ethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (R,R)-(2-ethoxycarbonylaminocyclohexyl)carbamic acid ethyl ester

There total 8 articles about (R,R)-(2-ethoxycarbonylaminocyclohexyl)carbamic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

chloroformic acid ethyl ester (541-41-3) + (1R,2R)-1,2-diaminocyclohexane tartrate (32044-22-7,39961-95-0) → (R,R)-(2-ethoxycarbonylaminocyclohexyl)carbamic acid ethyl ester (75730-13-1)

Guidance literature:

With sodium hydroxide; In water; toluene; at 0 - 20 ℃;

DOI:10.1016/j.tetasy.2010.03.001

Reference yield: 89.0%

(1R,2R)-1,2-diaminocyclohexane (20439-47-8) + chloroformic acid ethyl ester (541-41-3) → (R,R)-(2-ethoxycarbonylaminocyclohexyl)carbamic acid ethyl ester (75730-13-1)

Guidance literature:

With sodium hydroxide; In water; toluene; cooling;

DOI:10.1016/j.tetasy.2007.10.044

Reference yield: 86.0%

diethyl 7,8-diazabicyclo[4.2.0]oct-1-ene-7,8-dicarboxylate (1273252-60-0) → diethyl (1RS,2SR)-cyclohexane-1,2-diylbiscarbamate (75730-13-1,86694-16-8,116836-89-6)

Guidance literature:

With LiDBB; In tetrahydrofuran; at -78 - 20 ℃; Inert atmosphere;

DOI:10.1021/ol200193n

upstream raw materials:

(1R,2R)-1,2-diaminocyclohexane

chloroformic acid ethyl ester

(1R,2R)-1,2-diaminocyclohexane tartrate

diethyl 7,8-diazabicyclo[4.2.0]oct-1-ene-7,8-dicarboxylate

Downstream raw materials:

(R,R)-N,N'-dimethyl-1,2-diaminocyclohexane

(-)-N,N'-(dimethyl-d6)-1,2-diaminocyclohexane

(3aR,7aR)-2-<(1R)-methyl-3-tert-butyldiphenylsilyloxybutane>-<3a,4,5,6,7,7a-octa-hydro-1,3-dimethyl-1,3,2-benzodiazaphosphole>-2-oxide

(3aR,7aR)-2<(1R)-methyl-2-phenylethyl>-<3a,4,5,6,7,7a-octahydro-1,3-dimethyl-1,3,2-benzodiazaphosphole>-2-oxide