Cyclohexene, 1-(3-methoxy-1-propynyl)- (9CI)

Base Information

• Chemical Name: Cyclohexene, 1-(3-methoxy-1-propynyl)- (9CI)
• CAS No.: 227006-86-2
• Molecular Formula: C10H14 O
• Molecular Weight: 150.21756
• Mol file: 227006-86-2.mol

Synonyms:Cyclohexene,1-(3-methoxy-1-propynyl)- (9CI)

Chemical Property of Cyclohexene, 1-(3-methoxy-1-propynyl)- (9CI)

Chemical Property:

• PSA: 9.23000
• LogP: 2.13660

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Cyclohexene, 1-(3-methoxy-1-propynyl)- (9CI)

There total 1 articles about Cyclohexene, 1-(3-methoxy-1-propynyl)- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

1-ethenylcyclohexene (931-49-7) + chloromethyl methyl ether (107-30-2) → 1-(3-methoxy-2-propenyl)cyclohexene (227006-86-2)

Guidance literature:

1-ethenylcyclohexene; With n-butyllithium; In tetrahydrofuran; at -78 ℃; for 0.5h; Inert atmosphere;

chloromethyl methyl ether; at 20 ℃; for 1.5h; Inert atmosphere;

DOI:10.1021/acs.joc.9b02628

Reference yield: 72.0%

phenylmagnesium bromide (100-58-3) + 1-(3-methoxy-2-propenyl)cyclohexene (227006-86-2) → (1-(cyclohex-1-en-1-yl)propa-1,2-dien-1-yl)benzene

Guidance literature:

With copper(I) bromide; In diethyl ether; at -30 - 20 ℃; for 15h; Inert atmosphere;

DOI:10.1021/acs.joc.9b02628

Reference yield:

carbon monoxide (201230-82-2) + 1-(3-methoxy-2-propenyl)cyclohexene (227006-86-2) → (E)-2-Cyclohex-1-enyl-4-methoxy-but-2-enal + 2-cyclohex-1-enyl-4-methoxy-butyraldehyde + (E)-3-Cyclohex-1-enyl-2-methoxymethyl-propenal

Guidance literature:

With triphenyl phosphite; Rh(1+)(1,5-cyclooctadiene)(η6-C6H5B(1-)Ph3); hydrogen; In dichloromethane; at 60 ℃; for 48h; under 9120 Torr; Yield given; Yields of byproduct given;

DOI:10.1021/jo982425y

upstream raw materials:

1-ethenylcyclohexene

chloromethyl methyl ether

Refernces

• 1、 Bartko, Samuel G.,Hamzik, Phillip J.,Espindola, Leandro,Gomez, Christian,Danheiser, Rick L.. "Synthesis of Highly Substituted Pyridines via [4 + 2] Cycloadditions of Vinylallenes and Sulfonyl Cyanides". . p. 548 - 563. Retrieved 2020.