3-Fluoro-5-methylbenzene-1,2-diamine

Base Information

Chemical Name:3-Fluoro-5-methylbenzene-1,2-diamine
CAS No.:168966-55-0
Molecular Formula:C₇H₉FN₂
Molecular Weight:140.16
Hs Code.:
DSSTox Substance ID:DTXSID201289849

Synonyms:3-fluoro-5-methylbenzene-1,2-diamine;168966-55-0;SCHEMBL404462;DTXSID201289849;AKOS006309286;3-Fluoro-5-methyl-1,2-benzenediamine;EN300-194759

Suppliers and Price of 3-Fluoro-5-methylbenzene-1,2-diamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemicals and raw materials
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Total 1 raw suppliers

Chemical Property of 3-Fluoro-5-methylbenzene-1,2-diamine

Chemical Property:

XLogP3:1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:140.07497646
Heavy Atom Count:10
Complexity:118

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=CC(=C(C(=C1)F)N)N

Technology Process of 3-Fluoro-5-methylbenzene-1,2-diamine

There total 3 articles about 3-Fluoro-5-methylbenzene-1,2-diamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 449774-77-0
2-fluoro-4-methyl-6-nitroaniline

: 168966-55-0
1-fluoro-5-methyl-2,3-diaminobenzene

Guidance literature:: With hydrogen; 5percent Pd/C; In N,N-dimethyl-formamide; under 2689.24 Torr;
DOI:10.1021/jo025884e

Reference yield:

: 452-80-2
2-fluoro-4-methylaniline

: 168966-55-0
1-fluoro-5-methyl-2,3-diaminobenzene

Guidance literature:: Multi-step reaction with 3 steps

1.1: 94 percent / CHCl₃ / 0.67 h

2.1: aq. nitric acid / 2 h / 0 °C

2.2: 1.50 g / potassium hydroxide / methanol

3.1: 95 percent / hydrogen / 5percent Pd/C / dimethylformamide / 2689.24 Torr

With hydrogen; nitric acid; 5percent Pd/C; In chloroform; N,N-dimethyl-formamide;
DOI:10.1021/jo025884e

Reference yield:

: 326-67-0
N-(2-fluoro-4-methylphenyl)acetamide

: 168966-55-0
1-fluoro-5-methyl-2,3-diaminobenzene

Guidance literature:: Multi-step reaction with 2 steps

1.1: aq. nitric acid / 2 h / 0 °C

1.2: 1.50 g / potassium hydroxide / methanol

2.1: 95 percent / hydrogen / 5percent Pd/C / dimethylformamide / 2689.24 Torr

With hydrogen; nitric acid; 5percent Pd/C; In N,N-dimethyl-formamide;
DOI:10.1021/jo025884e