C₁₅H₁₆N₂O₂

Base Information

• Chemical Name: C₁₅H₁₆N₂O₂
• CAS No.: 953730-41-1
• Molecular Formula: C₁₅H₁₆N₂O₂
• Molecular Weight: 256.304
• Mol file: 953730-41-1.mol

Synonyms:C₁₅H₁₆N₂O₂

Chemical Property of C₁₅H₁₆N₂O₂

Chemical Property:

Purity/Quality:

98%min ^*data from raw suppliers

N-(3-Aminophenyl)-2-ethoxybenzamide ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi

MSDS Files:

Useful:

Technology Process of C₁₅H₁₆N₂O₂

There total 3 articles about C₁₅H₁₆N₂O₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C15H14N2O4 (349122-10-7) → C15H16N2O2 (953730-41-1)

Guidance literature:

With sodium tetrahydroborate; In methanol; dichloromethane; at 0 - 20 ℃; for 3h;

DOI:10.1016/j.bmcl.2014.06.032

Reference yield:

3-nitro-aniline (99-09-2) → C15H16N2O2 (953730-41-1)

Guidance literature:

Multi-step reaction with 2 steps

1: triethylamine / acetonitrile / 3 h / 75 °C

2: sodium tetrahydroborate / methanol; dichloromethane / 3 h / 0 - 20 °C

With sodium tetrahydroborate; triethylamine; In methanol; dichloromethane; acetonitrile;

DOI:10.1016/j.bmcl.2014.06.032

Reference yield:

2-ethoxybenzoyl chloride (42926-52-3) → C15H16N2O2 (953730-41-1)

Guidance literature:

Multi-step reaction with 2 steps

1: triethylamine / acetonitrile / 3 h / 75 °C

2: sodium tetrahydroborate / methanol; dichloromethane / 3 h / 0 - 20 °C

With sodium tetrahydroborate; triethylamine; In methanol; dichloromethane; acetonitrile;

DOI:10.1016/j.bmcl.2014.06.032

upstream raw materials:

C₁₅H₁₄N₂O₄

3-nitro-aniline

2-ethoxybenzoyl chloride

Downstream raw materials:

C₂₃H₁₉F₃N₂O₃

Refernces