(R)-(+)-4-Isopropyl-5,5-dimethyl-2-oxazolidinone

Base Information Edit

Chemical Name:(R)-(+)-4-Isopropyl-5,5-dimethyl-2-oxazolidinone
CAS No.:223906-38-5
Molecular Formula:C8H15 N O2
Molecular Weight:157.213
Hs Code.:2934999090
DSSTox Substance ID:DTXSID90441988
Nikkaji Number:J1.092.500B
Wikidata:Q82259022
Mol file:223906-38-5.mol

Synonyms:223906-38-5;(R)-(+)-4-Isopropyl-5,5-dimethyl-2-oxazolidinone;(R)-4-Isopropyl-5,5-dimethyloxazolidin-2-one;(4R)-5,5-dimethyl-4-propan-2-yl-1,3-oxazolidin-2-one;SCHEMBL2365869;DTXSID90441988;QICFUFOXXNIZFF-ZCFIWIBFSA-N;AKOS025294939;CS-0112377;4alpha-Isopropyl-5,5-dimethyloxazolidine-2-one;(R)-(+)-4-isopropyl-5,5-dimethyloxazolidin-2-one;J-014686;(R)-(+)-4-Isopropyl-5,5-dimethyl-2-oxazolidinone, 98%;(4R)-5,5-dimethyl-4-(propan-2-yl)-1,3-oxazolidin-2-one

Suppliers and Price of (R)-(+)-4-Isopropyl-5,5-dimethyl-2-oxazolidinone

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
(R)-(+)-4-Isopropyl-5,5-dimethyl-2-oxazolidinone 98%
250mg
$ 144.00

American Custom Chemicals Corporation
(R)-(+)-4-ISOPROPYL-5,5-DIMETHYL-2-OXAZOLIDINONE 95.00%
5G
$ 3817.80

American Custom Chemicals Corporation
(R)-(+)-4-ISOPROPYL-5,5-DIMETHYL-2-OXAZOLIDINONE 95.00%
1G
$ 736.14

American Custom Chemicals Corporation
(R)-(+)-4-ISOPROPYL-5,5-DIMETHYL-2-OXAZOLIDINONE 95.00%
250MG
$ 685.81

Total 4 raw suppliers

Chemical Property of (R)-(+)-4-Isopropyl-5,5-dimethyl-2-oxazolidinone Edit

Chemical Property:

Vapor Pressure:0.003mmHg at 25°C
Melting Point:86-87 °C(lit.)
Refractive Index:1.431
Boiling Point:284.2°Cat760mmHg
PKA:12.80±0.60(Predicted)
Flash Point:125.7°C
PSA：41.82000
Density:0.965g/cm³
LogP:1.16940
XLogP3:1.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:157.110278721
Heavy Atom Count:11
Complexity:175

Purity/Quality:

NLT 98% ^*data from raw suppliers

(R)-(+)-4-Isopropyl-5,5-dimethyl-2-oxazolidinone 98% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:F,Xi
Statements: 11-36/37/38
Safety Statements: 16-26-36

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:CC(C)C1C(OC(=O)N1)(C)C
Isomeric SMILES:CC(C)[C@@H]1C(OC(=O)N1)(C)C

Technology Process of (R)-(+)-4-Isopropyl-5,5-dimethyl-2-oxazolidinone

There total 8 articles about (R)-(+)-4-Isopropyl-5,5-dimethyl-2-oxazolidinone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 223906-58-9
(4R)-N-<(2S)-2-Methyl-1-oxo-3-phenylpropyl>-5,5-dimethyl-4-isopropyloxazolidin-2-one

: 1009-67-2,5628-72-8,14367-54-5,14367-67-0
2-methyl-3-phenylpropionic acid

: 223906-38-5
(4R)-5,5-dimethyl-4-(propan-2-yl)-1,3-oxazolidin-2-one

Guidance literature:: With lithium hydroxide; water; In tetrahydrofuran; for 24h; Ambient temperature;
DOI:10.1039/a809715a

Reference yield: 55.0%

: 1396008-67-5
C₄₀H₆₁N₃O₅

: 1021487-41-1
(-)-(S)-nakinadine B

: 223906-38-5
(4R)-5,5-dimethyl-4-(propan-2-yl)-1,3-oxazolidin-2-one

Guidance literature:: C₄₀H₆₁N₃O₅; With dihydrogen peroxide; lithium hydroxide; In tetrahydrofuran; at 0 - 20 ℃; for 16h;

With hydrogenchloride; In diethyl ether; at 20 ℃; for 0.5h;
DOI:10.1039/c2cc34808j

Reference yield:

: C₄₁H₆₁N₃O₅

: 1021486-53-2
(S)-2-phenyl-3-{N-[14-(pyridin-3-yl)tetradec-11-enyl]amino}propanoic acid

: 223906-38-5
(4R)-5,5-dimethyl-4-(propan-2-yl)-1,3-oxazolidin-2-one

Guidance literature:: C₄₁H₆₁N₃O₅; With dihydrogen peroxide; lithium hydroxide; In tetrahydrofuran; water; at 0 - 20 ℃; for 16h;

With hydrogenchloride; In diethyl ether; at 20 ℃; for 0.5h;
DOI:10.1016/j.tetlet.2013.09.043