6-chloro-4-((2-methoxy-3-(4H-1,2,4-triazol-3-yl)phenyl)amino)-N-methylnicotinamide

Base Information

Chemical Name:6-chloro-4-((2-methoxy-3-(4H-1,2,4-triazol-3-yl)phenyl)amino)-N-methylnicotinamide
CAS No.:1609531-46-5
Molecular Formula:C₁₆H₁₅ClN₆O₂
Molecular Weight:358.787
Hs Code.:

Synonyms:6-chloro-4-((2-methoxy-3-(4H-1,2,4-triazol-3-yl)phenyl)amino)-N-methylnicotinamide

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Chemical Property of 6-chloro-4-((2-methoxy-3-(4H-1,2,4-triazol-3-yl)phenyl)amino)-N-methylnicotinamide

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Technology Process of 6-chloro-4-((2-methoxy-3-(4H-1,2,4-triazol-3-yl)phenyl)amino)-N-methylnicotinamide

There total 6 articles about 6-chloro-4-((2-methoxy-3-(4H-1,2,4-triazol-3-yl)phenyl)amino)-N-methylnicotinamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 1609531-45-4
4-((3-carbamoyl-2-methoxyphenyl)amino)-6-chloro-N-methylnicotinamide

: 68-12-2,33513-42-7
N,N-dimethyl-formamide

: 1609531-46-5
6-chloro-4-((2-methoxy-3-(4H-1,2,4-triazol-3-yl)phenyl)amino)-N-methylnicotinamide

Guidance literature:: 4-((3-carbamoyl-2-methoxyphenyl)amino)-6-chloro-N-methylnicotinamide; N,N-dimethyl-formamide; In N,N-dimethyl acetamide; at 110 ℃; for 3h;

With hydrazine hydrate; acetic acid; In ethanol; at -10 - 20 ℃; Cooling with ice;

Reference yield: 87.0%

: 1609531-46-5
6-chloro-4-((2-methoxy-3-(4H-1,2,4-triazol-3-yl)phenyl)amino)-N-methylnicotinamide

Guidance literature:: at 110 ℃; for 0.5h;

With hydrazine hydrate; acetic acid; In ethanol; at -10 - 60 ℃;

Reference yield:

: 1609531-45-4
4-((3-carbamoyl-2-methoxyphenyl)amino)-6-chloro-N-methylnicotinamide

: 4637-24-5
N,N-dimethyl-formamide dimethyl acetal

: 1609531-46-5
6-chloro-4-((2-methoxy-3-(4H-1,2,4-triazol-3-yl)phenyl)amino)-N-methylnicotinamide

Guidance literature:: 4-((3-carbamoyl-2-methoxyphenyl)amino)-6-chloro-N-methylnicotinamide; N,N-dimethyl-formamide dimethyl acetal; at 110 ℃; for 3h;

With acetic acid; hydrazine; In ethanol; at -10 - 20 ℃;