(S,E)-5-phenyl-1-((4-(prop-2-yn-1-yloxy)phenyl)sulfonyl)pent-1-en-3-amine trifluoroacetate

Base Information

Chemical Name:(S,E)-5-phenyl-1-((4-(prop-2-yn-1-yloxy)phenyl)sulfonyl)pent-1-en-3-amine trifluoroacetate
CAS No.:1354894-27-1
Molecular Formula:C₂HF₃O₂*C₂₀H₂₁NO₃S
Molecular Weight:469.482
Hs Code.:

Synonyms:(S,E)-5-phenyl-1-((4-(prop-2-yn-1-yloxy)phenyl)sulfonyl)pent-1-en-3-amine trifluoroacetate

Suppliers and Price of (S,E)-5-phenyl-1-((4-(prop-2-yn-1-yloxy)phenyl)sulfonyl)pent-1-en-3-amine trifluoroacetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (S,E)-5-phenyl-1-((4-(prop-2-yn-1-yloxy)phenyl)sulfonyl)pent-1-en-3-amine trifluoroacetate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (S,E)-5-phenyl-1-((4-(prop-2-yn-1-yloxy)phenyl)sulfonyl)pent-1-en-3-amine trifluoroacetate

There total 6 articles about (S,E)-5-phenyl-1-((4-(prop-2-yn-1-yloxy)phenyl)sulfonyl)pent-1-en-3-amine trifluoroacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 82732-07-8,108524-68-1,142926-43-0,100564-78-1
Boc-L-homophenylalanine

: 1354894-27-1
(S,E)-5-phenyl-1-((4-(prop-2-yn-1-yloxy)phenyl)sulfonyl)pent-1-en-3-amine trifluoroacetate

Guidance literature:: Multi-step reaction with 4 steps

1: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine / tetrahydrofuran / 12 h / 0 - 20 °C / Inert atmosphere

2: lithium aluminium tetrahydride / tetrahydrofuran / 0.5 h / 0 °C / Inert atmosphere

3: sodium hydride / tetrahydrofuran; mineral oil / Inert atmosphere

4: dichloromethane / 2 h / 0 °C / Inert atmosphere

With lithium aluminium tetrahydride; sodium hydride; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; dichloromethane; mineral oil;
DOI:10.1039/c1cc16178d

Reference yield:

: 1354894-24-8
diethyl (((4-(prop-2-yn-1-yloxy)phenyl)sulfonyl)methyl)phosphonate

: 1354894-27-1
(S,E)-5-phenyl-1-((4-(prop-2-yn-1-yloxy)phenyl)sulfonyl)pent-1-en-3-amine trifluoroacetate

Guidance literature:: Multi-step reaction with 2 steps

1: sodium hydride / tetrahydrofuran; mineral oil / Inert atmosphere

2: dichloromethane / 2 h / 0 °C / Inert atmosphere

With sodium hydride; In tetrahydrofuran; dichloromethane; mineral oil;
DOI:10.1039/c1cc16178d

Reference yield:

: 211518-82-0
4-hydroxy-thiophenyl-methyl-diethylphosphonate sulfone

: 1354894-27-1
(S,E)-5-phenyl-1-((4-(prop-2-yn-1-yloxy)phenyl)sulfonyl)pent-1-en-3-amine trifluoroacetate

Guidance literature:: Multi-step reaction with 3 steps

1.1: potassium carbonate / acetone / 2 h / 20 °C / Inert atmosphere

1.2: 12 h / Inert atmosphere

2.1: sodium hydride / tetrahydrofuran; mineral oil / Inert atmosphere

3.1: dichloromethane / 2 h / 0 °C / Inert atmosphere

With sodium hydride; potassium carbonate; In tetrahydrofuran; dichloromethane; acetone; mineral oil;
DOI:10.1039/c1cc16178d