13-(phenylthio)alantolactone

Base Information

• Chemical Name: 13-(phenylthio)alantolactone
• CAS No.: 123489-73-6
• Molecular Formula: C₂₁H₂₆O₂S
• Molecular Weight: 342.502
• Mol file: 123489-73-6.mol

Synonyms:13-(phenylthio)alantolactone

Chemical Property of 13-(phenylthio)alantolactone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of 13-(phenylthio)alantolactone

There total 2 articles about 13-(phenylthio)alantolactone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

thiophenol (108-98-5) + alantolactone (546-43-0) → 13-(phenylthio)alantolactone (123489-73-6)

Guidance literature:

With triethylamine; In methanol; at 20 ℃; for 0.166667h;

DOI:10.1134/S106816202104018X

Reference yield: 95.0%

sodium thiophenolate (930-69-8) + alantolactone (546-43-0) → 13-(phenylthio)alantolactone (123489-73-6)

Guidance literature:

In ethanol; for 2h; Ambient temperature;

DOI:10.1021/jo00287a024

Reference yield: 85.0%

13-(phenylthio)alantolactone (123489-73-6) → (3aR,5S,8aR,9aR)-3-Benzenesulfinylmethyl-5,8a-dimethyl-3a,5,6,7,8,8a,9,9a-octahydro-3H-naphtho[2,3-b]furan-2-one

Guidance literature:

With 3-chloro-benzenecarboperoxoic acid; In dichloromethane; at -15 - -5 ℃;

DOI:10.1021/jo00287a024

upstream raw materials:

sodium thiophenolate

alantolactone

thiophenol

Downstream raw materials:

(3aR,5S,8aR,9aR)-5,8a-Dimethyl-3-[1-phenylsulfanyl-meth-(E)-ylidene]-3a,5,6,7,8,8a,9,9a-octahydro-3H-naphtho[2,3-b]furan-2-one

(3aR,5S,8aR,9aR)-5,8a-Dimethyl-3-[1-phenylsulfanyl-meth-(Z)-ylidene]-3a,5,6,7,8,8a,9,9a-octahydro-3H-naphtho[2,3-b]furan-2-one

Refernces

• 1、 Schaeffer, Marcel,Stampf, Jean-Luc,Benezra, Claude. "Synthesis of Deuterium-Labeled Sesquiterpene Lactones Isolated from Inula helenium L.". . p. 6106 - 6113. Retrieved 2007/10/02.