isopropyl 4-((1R)-1-(2-amino-2-(3,5-dichlorophenyl)acetamido)-4,4-dimethylpentyl)benzoate

Base Information

Chemical Name:isopropyl 4-((1R)-1-(2-amino-2-(3,5-dichlorophenyl)acetamido)-4,4-dimethylpentyl)benzoate
CAS No.:1220903-13-8
Molecular Formula:C₂₅H₃₂Cl₂N₂O₃
Molecular Weight:479.447
Hs Code.:

Synonyms:isopropyl 4-((1R)-1-(2-amino-2-(3,5-dichlorophenyl)acetamido)-4,4-dimethylpentyl)benzoate

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Chemical Property of isopropyl 4-((1R)-1-(2-amino-2-(3,5-dichlorophenyl)acetamido)-4,4-dimethylpentyl)benzoate

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Technology Process of isopropyl 4-((1R)-1-(2-amino-2-(3,5-dichlorophenyl)acetamido)-4,4-dimethylpentyl)benzoate

There total 7 articles about isopropyl 4-((1R)-1-(2-amino-2-(3,5-dichlorophenyl)acetamido)-4,4-dimethylpentyl)benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 1220903-12-7
isopropyl 4-((1R)-1-(2-(tert-butoxycarbonylamino)-2-(3,5-dichlorophenyl)acetamido)-3,3-dimethylbutyl)-benzoate

: 1220903-13-8
isopropyl 4-((1R)-1-(2-amino-2-(3,5-dichlorophenyl)acetamido)-4,4-dimethylpentyl)benzoate

Guidance literature:: isopropyl 4-((1R)-1-(2-(tert-butoxycarbonylamino)-2-(3,5-dichlorophenyl)acetamido)-3,3-dimethylbutyl)-benzoate; With trifluoroacetic acid; In dichloromethane; at 25 ℃; for 18h;

With sodium hydroxide; In dichloromethane; water;

Reference yield:

: 1336888-76-6
(R)-isopropyl 4-(1-amino-4,4-dimethylpentyl)benzoate hydrochloride

: 1220903-13-8
isopropyl 4-((1R)-1-(2-amino-2-(3,5-dichlorophenyl)acetamido)-4,4-dimethylpentyl)benzoate

Guidance literature:: Multi-step reaction with 2 steps

1: N-ethyl-N,N-diisopropylamine; benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate / acetonitrile / 18 h / 25 °C

2: trifluoroacetic acid / dichloromethane / 18 h / 25 °C

With benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid; In dichloromethane; acetonitrile;

Reference yield:

: 369403-30-5
2-((tert-butoxycarbonyl)amino)-2-(3,5-dichlorophenyl)acetic acid

: 1220903-13-8
isopropyl 4-((1R)-1-(2-amino-2-(3,5-dichlorophenyl)acetamido)-4,4-dimethylpentyl)benzoate

Guidance literature:: Multi-step reaction with 2 steps

1: N-ethyl-N,N-diisopropylamine; benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate / acetonitrile / 18 h / 25 °C

2: trifluoroacetic acid / dichloromethane / 18 h / 25 °C

With benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid; In dichloromethane; acetonitrile;