α-(N-ethoxycarbonylamidrazonyl)-α-phenylhydrazonoacetamide hydrochloride

Base Information

• Chemical Name: α-(N-ethoxycarbonylamidrazonyl)-α-phenylhydrazonoacetamide hydrochloride
• CAS No.: 115998-44-2
• Molecular Formula: C₁₂H₁₆N₆O₃*ClH
• Molecular Weight: 328.758
• Mol file: 115998-44-2.mol

Synonyms:α-(N-ethoxycarbonylamidrazonyl)-α-phenylhydrazonoacetamide hydrochloride

Chemical Property of α-(N-ethoxycarbonylamidrazonyl)-α-phenylhydrazonoacetamide hydrochloride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of α-(N-ethoxycarbonylamidrazonyl)-α-phenylhydrazonoacetamide hydrochloride

There total 3 articles about α-(N-ethoxycarbonylamidrazonyl)-α-phenylhydrazonoacetamide hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

chloroformic acid ethyl ester (541-41-3) + α-carboxamido-α-phenylhydrazonoacetamidrazone (115998-40-8) → α-(N-ethoxycarbonylamidrazonyl)-α-phenylhydrazonoacetamide hydrochloride (115998-44-2)

Guidance literature:

In ethanol; for 3h; Heating;

Reference yield:

benzene diazonium chloride (100-34-5) → α-(N-ethoxycarbonylamidrazonyl)-α-phenylhydrazonoacetamide hydrochloride (115998-44-2)

Guidance literature:

Multi-step reaction with 3 steps

1: 80 percent / sodium acetate / ethanol; H₂O / 2 h / Ambient temperature

2: 65 percent / hydrazine hydrate / ethanol / 1 h / Heating

3: 68 percent / ethanol / 3 h / Heating

With sodium acetate; hydrazine hydrate; In ethanol; water;

Reference yield:

α-carboxamido-α-phenylhydrazonoacetonitrile (20923-20-0) → α-(N-ethoxycarbonylamidrazonyl)-α-phenylhydrazonoacetamide hydrochloride (115998-44-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 65 percent / hydrazine hydrate / ethanol / 1 h / Heating

2: 68 percent / ethanol / 3 h / Heating

With hydrazine hydrate; In ethanol;

upstream raw materials:

chloroformic acid ethyl ester

α-carboxamido-α-phenylhydrazonoacetamidrazone

benzene diazonium chloride

α-carboxamido-α-phenylhydrazonoacetonitrile

Downstream raw materials:

5--1,2,4-triazol-3-one

Refernces