tert-butyl 6-(4-(5-(2,4-bis(benzyloxy)-5-isopropylphenyl)-3-(ethylcarbamoyl)isoxazol-4-yl)benzylamino)hexylcarbamate

Base Information

• Chemical Name: tert-butyl 6-(4-(5-(2,4-bis(benzyloxy)-5-isopropylphenyl)-3-(ethylcarbamoyl)isoxazol-4-yl)benzylamino)hexylcarbamate
• CAS No.: 1301630-39-6
• Molecular Formula: C₄₇H₅₈N₄O₆
• Molecular Weight: 775.001

Synonyms:tert-butyl 6-(4-(5-(2,4-bis(benzyloxy)-5-isopropylphenyl)-3-(ethylcarbamoyl)isoxazol-4-yl)benzylamino)hexylcarbamate

Chemical Property of tert-butyl 6-(4-(5-(2,4-bis(benzyloxy)-5-isopropylphenyl)-3-(ethylcarbamoyl)isoxazol-4-yl)benzylamino)hexylcarbamate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of tert-butyl 6-(4-(5-(2,4-bis(benzyloxy)-5-isopropylphenyl)-3-(ethylcarbamoyl)isoxazol-4-yl)benzylamino)hexylcarbamate

There total 3 articles about tert-butyl 6-(4-(5-(2,4-bis(benzyloxy)-5-isopropylphenyl)-3-(ethylcarbamoyl)isoxazol-4-yl)benzylamino)hexylcarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

5-(2,4-bis(benzyloxy)-5-isopropylphenyl)-4-(4-formylphenyl)isoxazole-3-carboxylic acid ethylamide (747414-23-9) + tert-butyl N-(6-aminohexyl)carbamate (51857-17-1) → tert-butyl 6-(4-(5-(2,4-bis(benzyloxy)-5-isopropylphenyl)-3-(ethylcarbamoyl)isoxazol-4-yl)benzylamino)hexylcarbamate (1301630-39-6)

Guidance literature:

With sodium cyanoborohydride; acetic acid; In dichloromethane; at 20 ℃; for 1h; Molecular sieve;

DOI:10.1016/j.bmc.2011.03.013

Reference yield:

1,6-Hexanediamine (124-09-4) → tert-butyl 6-(4-(5-(2,4-bis(benzyloxy)-5-isopropylphenyl)-3-(ethylcarbamoyl)isoxazol-4-yl)benzylamino)hexylcarbamate (1301630-39-6)

Guidance literature:

Multi-step reaction with 2 steps

1: triethylamine / dichloromethane / 18 h / 20 °C

2: sodium cyanoborohydride; acetic acid / dichloromethane / 1 h / 20 °C / Molecular sieve

With sodium cyanoborohydride; acetic acid; triethylamine; In dichloromethane;

DOI:10.1016/j.bmc.2011.03.013

Reference yield:

di-tert-butyl dicarbonate (24424-99-5) → tert-butyl 6-(4-(5-(2,4-bis(benzyloxy)-5-isopropylphenyl)-3-(ethylcarbamoyl)isoxazol-4-yl)benzylamino)hexylcarbamate (1301630-39-6)

Guidance literature:

Multi-step reaction with 2 steps

1: triethylamine / dichloromethane / 18 h / 20 °C

2: sodium cyanoborohydride; acetic acid / dichloromethane / 1 h / 20 °C / Molecular sieve

With sodium cyanoborohydride; acetic acid; triethylamine; In dichloromethane;

DOI:10.1016/j.bmc.2011.03.013

upstream raw materials:

1,6-Hexanediamine

5-(2,4-bis(benzyloxy)-5-isopropylphenyl)-4-(4-formylphenyl)isoxazole-3-carboxylic acid ethylamide

tert-butyl N-(6-aminohexyl)carbamate

di-tert-butyl dicarbonate

Downstream raw materials:

4-(4-((6-aminohexylamino)methyl)phenyl)-5-(2,4-dihydroxy-5-isopropylphenyl)-N-ethylisoxazole-3-carboxamide

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 1301630-39-6 tert-butyl 6-(4-(5-(2,4-bis(benzyloxy)-5-isopropylphenyl)-3-(ethylcarbamoyl)isoxazol-4-yl)benzylamino)hexylcarbamate

Send

Send

Metric Ton KG G Pound L ML

Send

Send