Methyl 1-((2-Benzyloxycarbonxyl)phenyl)-2,3,4-tri-O-acetyl--D-glucopyranuronate

Base Information

Chemical Name:Methyl 1-((2-Benzyloxycarbonxyl)phenyl)-2,3,4-tri-O-acetyl--D-glucopyranuronate
CAS No.:221287-88-3
Molecular Formula:C27H28 O12
Molecular Weight:544.5
Hs Code.:
Mol file:221287-88-3.mol

Synonyms:2-[(Phenylmethoxy)carbonyl]phenyl -D-Glucopyranosiduronic Acid Methyl Ester Triacetate;Methyl 1-((2-Benzyloxycarbonxyl)phenyl)-2,3,4-tri-O-acetyl--D-glucopyranuronate

Suppliers and Price of Methyl 1-((2-Benzyloxycarbonxyl)phenyl)-2,3,4-tri-O-acetyl--D-glucopyranuronate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Methyl1-((2-Benzyloxycarbonxyl)phenyl)-2,3,4-tri-O-acetyl-β-D-glucopyranuronate
10mg
$ 110.00

American Custom Chemicals Corporation
METHYL 1-((2-BENZYLOXYCARBONXYL)PHENYL)-2,3,4-TRI-O-ACETYL-BETA-D-GLUCOPYRANURONATE 95.00%
5MG
$ 500.28

Total 2 raw suppliers

Chemical Property of Methyl 1-((2-Benzyloxycarbonxyl)phenyl)-2,3,4-tri-O-acetyl--D-glucopyranuronate

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Melting Point:131-135°C
Refractive Index:1.564
Boiling Point:612.873°C at 760 mmHg
Flash Point:258.702°C
PSA：160.96000
Density:1.347g/cm³
LogP:1.55560
Solubility.:Chloroform, Dichloromethane, Ether

Purity/Quality:

97% ^*data from raw suppliers

Methyl1-((2-Benzyloxycarbonxyl)phenyl)-2,3,4-tri-O-acetyl-β-D-glucopyranuronate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses An intermediate in the synthesis of the metabolite of Nitazoxanide An intermediate in the synthesis of the metabolite of Nitazoxanide.

Technology Process of Methyl 1-((2-Benzyloxycarbonxyl)phenyl)-2,3,4-tri-O-acetyl--D-glucopyranuronate

There total 1 articles about Methyl 1-((2-Benzyloxycarbonxyl)phenyl)-2,3,4-tri-O-acetyl--D-glucopyranuronate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.0%

: 118-58-1
benzyl salicylate

: 21085-72-3
1-bromo-2,3,4-tri-O-acetyl-α-D-glucuronic acid methyl ester

: 221287-88-3
methyl 1-<2-(benzyloxycarbonyl)phenyl>-2,3,4-tri-O-acetyl-β-D-glucopyranuronate

Guidance literature:: With isoquinoline; silver(l) oxide; at 20 ℃; for 1h;
DOI:10.1039/a806676k

Reference yield: 80.0%

: 221287-88-3
methyl 1-<2-(benzyloxycarbonyl)phenyl>-2,3,4-tri-O-acetyl-β-D-glucopyranuronate

: 221287-90-7
methyl 1-(2-carboxyphenyl)-2,3,4-tri-O-acetyl-β-D-glucopyranuronate

Guidance literature:: With cyclohexene; palladium on activated charcoal; In isopropyl alcohol; for 0.5h; Heating;
DOI:10.1039/a806676k

Reference yield:

: 221287-88-3
methyl 1-<2-(benzyloxycarbonyl)phenyl>-2,3,4-tri-O-acetyl-β-D-glucopyranuronate

: Tizoxanide glucuronide

Guidance literature:: Multi-step reaction with 3 steps

1: 80 percent / cyclohexene / Pd/C / propan-2-ol / 0.5 h / Heating

2: 67 percent / 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride, 4-N,N-dimethylaminopyridine, 1-hydroxybenzotriazole monohydrate / dimethylformamide / a) 20 deg C, 2 h, b) 0 deg C, 16 h

3: 89 percent / NaOH / methanol / 1 h / 20 °C

With dmap; sodium hydroxide; 1-hydroxybenzotriazol-hydrate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; cyclohexene; palladium on activated charcoal; In methanol; N,N-dimethyl-formamide; isopropyl alcohol;
DOI:10.1039/a806676k