6,9,12-tris(p-tolylsulfonyl)-6,9,12-triaza-1,17-bis<(tetrahydropyran-2-yl)oxy>heptadecane

Base Information

• Chemical Name: 6,9,12-tris(p-tolylsulfonyl)-6,9,12-triaza-1,17-bis<(tetrahydropyran-2-yl)oxy>heptadecane
• CAS No.: 76102-76-6
• Molecular Formula: C₄₅H₆₇N₃O₁₀S₃
• Molecular Weight: 906.239
• Mol file: 76102-76-6.mol

Synonyms:6,9,12-tris(p-tolylsulfonyl)-6,9,12-triaza-1,17-bis<(tetrahydropyran-2-yl)oxy>heptadecane

Chemical Property of 6,9,12-tris(p-tolylsulfonyl)-6,9,12-triaza-1,17-bis<(tetrahydropyran-2-yl)oxy>heptadecane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 6,9,12-tris(p-tolylsulfonyl)-6,9,12-triaza-1,17-bis<(tetrahydropyran-2-yl)oxy>heptadecane

There total 4 articles about 6,9,12-tris(p-tolylsulfonyl)-6,9,12-triaza-1,17-bis<(tetrahydropyran-2-yl)oxy>heptadecane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

N,N’,N”-tris(p-toluenesulfonyl)diethylenetriamine N,N-disodium salt (52601-80-6) + 1-<5-<2-(tetrahydropyranyloxy)>pentyl>methanesulfonate (76102-75-5) → 6,9,12-tris(p-tolylsulfonyl)-6,9,12-triaza-1,17-bis<(tetrahydropyran-2-yl)oxy>heptadecane (76102-76-6)

Guidance literature:

In N,N-dimethyl-formamide; at 95 ℃; for 2h;

DOI:10.1021/jo00342a007

Reference yield:

3,4-dihydro-2H-pyran (110-87-2) → 6,9,12-tris(p-tolylsulfonyl)-6,9,12-triaza-1,17-bis<(tetrahydropyran-2-yl)oxy>heptadecane (76102-76-6)

Guidance literature:

Multi-step reaction with 3 steps

1: conc. HCl

2: N(C₂H₅)3 / CH₂Cl₂ / 0.5 h

3: 90 percent / dimethylformamide / 2 h / 95 °C

With hydrogenchloride; triethylamine; In dichloromethane; N,N-dimethyl-formamide;

DOI:10.1021/jo00342a007

Reference yield:

5-(tetrahydro-2H-pyran-2-yloxy)pentan-1-ol (76102-74-4) → 6,9,12-tris(p-tolylsulfonyl)-6,9,12-triaza-1,17-bis<(tetrahydropyran-2-yl)oxy>heptadecane (76102-76-6)

Guidance literature:

Multi-step reaction with 2 steps

1: N(C₂H₅)3 / CH₂Cl₂ / 0.5 h

2: 90 percent / dimethylformamide / 2 h / 95 °C

With triethylamine; In dichloromethane; N,N-dimethyl-formamide;

DOI:10.1021/jo00342a007

upstream raw materials:

N,N’,N”-tris(p-toluenesulfonyl)diethylenetriamine N,N-disodium salt

1-<5-<2-(tetrahydropyranyloxy)>pentyl>methanesulfonate

3,4-dihydro-2H-pyran

5-(tetrahydro-2H-pyran-2-yloxy)pentan-1-ol

Downstream raw materials:

6,9,12-tris(p-tolylsulfonyl)-6,9,12-triazaheptadecane-1,17-diol

1,4,7,13,16,19-hexakis(p-tolylsulfonyl)-1,4,7,13,16,19-hexaazacyclotetracosane

6,9,12-tris(p-tolylsulfonyl)-6,9,12-triazaheptadecane-1,17-bis(methanesulfonate)