5'-O-(4,4'-dimethoxytrityl)thymidylyl-(3'-5'-carbamoyl)-5'-amino-3'-O-tert-butyldiphenylsilyl-2'-O,5'-N-cyclo-5'-deoxyarabinouridine

Base Information

Chemical Name:5'-O-(4,4'-dimethoxytrityl)thymidylyl-(3'-5'-carbamoyl)-5'-amino-3'-O-tert-butyldiphenylsilyl-2'-O,5'-N-cyclo-5'-deoxyarabinouridine
CAS No.:1138083-44-9
Molecular Formula:C₅₇H₅₉N₅O₁₃Si
Molecular Weight:1050.21
Hs Code.:

Synonyms:5'-O-(4,4'-dimethoxytrityl)thymidylyl-(3'-5'-carbamoyl)-5'-amino-3'-O-tert-butyldiphenylsilyl-2'-O,5'-N-cyclo-5'-deoxyarabinouridine

Suppliers and Price of 5'-O-(4,4'-dimethoxytrityl)thymidylyl-(3'-5'-carbamoyl)-5'-amino-3'-O-tert-butyldiphenylsilyl-2'-O,5'-N-cyclo-5'-deoxyarabinouridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 5'-O-(4,4'-dimethoxytrityl)thymidylyl-(3'-5'-carbamoyl)-5'-amino-3'-O-tert-butyldiphenylsilyl-2'-O,5'-N-cyclo-5'-deoxyarabinouridine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 5'-O-(4,4'-dimethoxytrityl)thymidylyl-(3'-5'-carbamoyl)-5'-amino-3'-O-tert-butyldiphenylsilyl-2'-O,5'-N-cyclo-5'-deoxyarabinouridine

There total 1 articles about 5'-O-(4,4'-dimethoxytrityl)thymidylyl-(3'-5'-carbamoyl)-5'-amino-3'-O-tert-butyldiphenylsilyl-2'-O,5'-N-cyclo-5'-deoxyarabinouridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1080623-54-6
3-N-benzyloxymethyl-5'-O-dimethoxytritylthymidylyl-(3'-5'-carbamoyl)-5'-amino-3-N-benzyloxymethyl-3'-O-tert-butyldiphenylsilyl-2'-O,5'-N-cyclo-5'-deoxyarabinouridine

: 1138083-44-9
5'-O-(4,4'-dimethoxytrityl)thymidylyl-(3'-5'-carbamoyl)-5'-amino-3'-O-tert-butyldiphenylsilyl-2'-O,5'-N-cyclo-5'-deoxyarabinouridine

Guidance literature:: 3-N-benzyloxymethyl-5'-O-dimethoxytritylthymidylyl-(3'-5'-carbamoyl)-5'-amino-3-N-benzyloxymethyl-3'-O-tert-butyldiphenylsilyl-2'-O,5'-N-cyclo-5'-deoxyarabinouridine; With boron trichloride; In dichloromethane; at -78 ℃; for 0.5h; Inert atmosphere;

With pyridine; 4,4'-dimethoxytrityl chloride; at 20 ℃; for 16h; Inert atmosphere;
DOI:10.1016/j.tet.2008.12.073

Reference yield: 97.0%

: 1138083-44-9
5'-O-(4,4'-dimethoxytrityl)thymidylyl-(3'-5'-carbamoyl)-5'-amino-3'-O-tert-butyldiphenylsilyl-2'-O,5'-N-cyclo-5'-deoxyarabinouridine

: 1080623-55-7
5'-O-(4,4'-dimethoxytrityl)thymidylyl-(3'-5'-carbamoyl)-5'-amino-2'-O,5'-N-cyclo-5'-deoxyarabinouridine

Guidance literature:: With tetrabutyl ammonium fluoride; In tetrahydrofuran; at 20 ℃; for 0.25h; Inert atmosphere;
DOI:10.1016/j.tet.2008.12.073