[3,3'-bis(trifluoromethyl)] diphenyl-N,N-bis((S,S)-1-phenyl-ethyl)phosphinamine

Base Information

• Chemical Name: [3,3'-bis(trifluoromethyl)] diphenyl-N,N-bis((S,S)-1-phenyl-ethyl)phosphinamine
• CAS No.: 959680-51-4
• Molecular Formula: C₃₀H₂₆F₆NP
• Molecular Weight: 545.507
• Mol file: 959680-51-4.mol

Synonyms:[3,3'-bis(trifluoromethyl)] diphenyl-N,N-bis((S,S)-1-phenyl-ethyl)phosphinamine

Chemical Property of [3,3'-bis(trifluoromethyl)] diphenyl-N,N-bis((S,S)-1-phenyl-ethyl)phosphinamine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of [3,3'-bis(trifluoromethyl)] diphenyl-N,N-bis((S,S)-1-phenyl-ethyl)phosphinamine

There total 3 articles about [3,3'-bis(trifluoromethyl)] diphenyl-N,N-bis((S,S)-1-phenyl-ethyl)phosphinamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

(C6H4CF3)2PBH3N(CH)2(CH3)2(C6H5)2 → [3,3'-bis(trifluoromethyl)] diphenyl-N,N-bis((S,S)-1-phenyl-ethyl)phosphinamine (959680-51-4)

Guidance literature:

With morpholine; In diethyl ether; at 20 ℃; for 48h; Inert atmosphere;

DOI:10.1002/chem.200901577

Reference yield:

3-(trifluoromethyl)phenylmagnesium bromide (402-26-6) + [(S,S)-bis(α-methylbenzyl)amino]phosphorous dichloride (777067-25-1) → [3,3'-bis(trifluoromethyl)] diphenyl-N,N-bis((S,S)-1-phenyl-ethyl)phosphinamine (959680-51-4)

Guidance literature:

In tetrahydrofuran; Heating;

DOI:10.1002/anie.200702186

Reference yield:

bis[3-(trifluoromethyl)phenyl]chlorophosphine (13685-25-1) + (1S,1'S)-bis(1-phenylethyl)amine (21003-56-5,21003-57-6,23294-41-9,42287-48-9,56210-72-1,10024-74-5) → [3,3'-bis(trifluoromethyl)] diphenyl-N,N-bis((S,S)-1-phenyl-ethyl)phosphinamine (959680-51-4)

Guidance literature:

(1S,1'S)-bis(1-phenylethyl)amine; With n-butyllithium; In tetrahydrofuran; hexane; at -78 - 20 ℃;

bis[3-(trifluoromethyl)phenyl]chlorophosphine; In tetrahydrofuran; hexane; at -78 - 20 ℃;

DOI:10.1002/chem.200901577

upstream raw materials:

3-(trifluoromethyl)phenylmagnesium bromide

[(S,S)-bis(α-methylbenzyl)amino]phosphorous dichloride

bis[3-(trifluoromethyl)phenyl]chlorophosphine

(1S,1'S)-bis(1-phenylethyl)amine