Technology Process of C21H21F2N7O2S
There total 8 articles about C21H21F2N7O2S which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
caesium carbonate;
copper(l) iodide; 3,4,7,8-Tetramethyl-o-phenanthrolin;
In
N,N-dimethyl-formamide;
at 105 ℃;
for 48h;
Inert atmosphere;
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: potassium fluoride / methanol / 45 °C
1.2: 72 h / 45 °C
2.1: caesium carbonate / copper(l) iodide; 3,4,7,8-Tetramethyl-o-phenanthrolin / N,N-dimethyl-formamide / 48 h / 105 °C / Inert atmosphere
With
potassium fluoride; caesium carbonate;
copper(l) iodide; 3,4,7,8-Tetramethyl-o-phenanthrolin;
In
methanol; N,N-dimethyl-formamide;
2.1: Buchwald-Hartwig coupling;
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: trifluoroacetic acid; sodium nitrite / 0.5 h / 0 °C
1.2: 1.25 h
2.1: potassium fluoride / methanol / 45 °C
2.2: 72 h / 45 °C
3.1: caesium carbonate / copper(l) iodide; 3,4,7,8-Tetramethyl-o-phenanthrolin / N,N-dimethyl-formamide / 48 h / 105 °C / Inert atmosphere
With
potassium fluoride; caesium carbonate; trifluoroacetic acid; sodium nitrite;
copper(l) iodide; 3,4,7,8-Tetramethyl-o-phenanthrolin;
In
methanol; N,N-dimethyl-formamide;
3.1: Buchwald-Hartwig coupling;