Technology Process of Quinoline, 3,8-diethoxy- (9CI)
There total 11 articles about Quinoline, 3,8-diethoxy- (9CI) which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
potassium hydroxide;
In
dimethyl sulfoxide;
at 60 ℃;
for 1h;
DOI:10.3987/com-98-8326
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 82 percent / lithium tetramethylpiperidide, trimethyl borate / tetrahydrofuran / 2 h / -75 °C
2: 90 percent / 32percent peracetic acid / acetic acid / 2 h / Ambient temperature
3: 95 percent / potassium carbonate / acetone / 1.5 h / Heating
4: 65 percent / Zn, AcOH / H2O / 1.5 h / 70 - 75 °C
5: 70 percent / pyridine hydrochloride / 1 h / 200 - 220 °C
6: 93 percent / KOH / dimethylsulfoxide / 1 h / 60 °C
With
peracetic acid; potassium hydroxide; Trimethyl borate; 2,2,6,6-tetramethylpiperidinyl-lithium; pyridine hydrochloride; potassium carbonate; acetic acid; zinc;
In
tetrahydrofuran; water; acetic acid; dimethyl sulfoxide; acetone;
DOI:10.3987/com-98-8326
- Guidance literature:
-
Multi-step reaction with 7 steps
1: 99 percent / phosphorus oxychloride, pyridine / chlorobenzene / 2 h / Heating
2: 82 percent / lithium tetramethylpiperidide, trimethyl borate / tetrahydrofuran / 2 h / -75 °C
3: 90 percent / 32percent peracetic acid / acetic acid / 2 h / Ambient temperature
4: 95 percent / potassium carbonate / acetone / 1.5 h / Heating
5: 65 percent / Zn, AcOH / H2O / 1.5 h / 70 - 75 °C
6: 70 percent / pyridine hydrochloride / 1 h / 200 - 220 °C
7: 93 percent / KOH / dimethylsulfoxide / 1 h / 60 °C
With
pyridine; peracetic acid; potassium hydroxide; Trimethyl borate; 2,2,6,6-tetramethylpiperidinyl-lithium; pyridine hydrochloride; potassium carbonate; acetic acid; zinc; trichlorophosphate;
In
tetrahydrofuran; water; acetic acid; dimethyl sulfoxide; chlorobenzene; acetone;
DOI:10.3987/com-98-8326
