3-Acetyl-2,4-dimethylfuran

Base Information

• Chemical Name: 3-Acetyl-2,4-dimethylfuran
• CAS No.: 32933-07-6
• Molecular Formula: C₈H₁₀O₂
• Molecular Weight: 138.166
• Hs Code.: 2932190090
• Mol file: 32933-07-6.mol

Synonyms:Ketone,2,4-dimethyl-3-furyl methyl (8CI); 3-Acetyl-2,4-dimethylfuran

Chemical Property of 3-Acetyl-2,4-dimethylfuran

Chemical Property:

• Boiling Point: 82-85 °C(Press: 11 Torr)
• PSA: 30.21000
• Density: 1.066 g/mL at 25 °C(lit.)
• LogP: 2.09900

Purity/Quality:

98%min ^*data from raw suppliers

3-ACETYL-2,4-DIMETHYLFURAN 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-Acetyl-2,4-dimethylfuran

There total 23 articles about 3-Acetyl-2,4-dimethylfuran which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

hydroxy-2-propanone (116-09-6) + acetylacetone (123-54-6,81235-32-7) → 1-(2,4-dimethyl-furan-3-yl)-ethanone (32933-07-6)

Guidance literature:

With zinc(II) chloride; In ethanol; for 1h; Heating;

DOI:10.3987/COM-97-8022

Reference yield: 77.0%

4-acetyl-5-methyl-3-methylene-2,3-dihydrofuran → 1-(2,4-dimethyl-furan-3-yl)-ethanone (32933-07-6)

Guidance literature:

With hydrogenchloride; In tetrahydrofuran; at 25 - 30 ℃; for 0.166667h;

DOI:10.1016/0022-328X(87)80052-9

Reference yield: 70.0%

1,2,3-tribromopropane (96-11-7) + acetylacetone (123-54-6,81235-32-7) → 1-(2,4-dimethyl-furan-3-yl)-ethanone (32933-07-6)

Guidance literature:

With potassium carbonate; In dimethyl sulfoxide; at 70 ℃; for 12h;

DOI:10.1007/BF00503618

upstream raw materials:

1-(2-Methoxy-2-methyl-4-methylene-tetrahydro-furan-3-yl)-ethanone

2-Bromo-4-acetyl-1-hexen-5-one

1,2,3-trichloropropane

acetylacetone

Downstream raw materials:

N-[1-(2',4'-dimethylfur-3'-yl)ethylidene]aniline

[1-(2,4-Dimethyl-furan-3-yl)-ethyl]-phenyl-amine

N-benzyloxycarbonyl-N-[1-(2',4'-dimethylfur-3'-yl)ethyl]aniline