1-(2-methylallyl)-4-(phenylthio)-6-(E-1-propenyl)-1,2,5,6-tetrahydro-2-pyridinone

Base Information

Chemical Name:1-(2-methylallyl)-4-(phenylthio)-6-(E-1-propenyl)-1,2,5,6-tetrahydro-2-pyridinone
CAS No.:1415683-63-4
Molecular Formula:C₁₈H₂₁NOS
Molecular Weight:299.437
Hs Code.:

Synonyms:1-(2-methylallyl)-4-(phenylthio)-6-(E-1-propenyl)-1,2,5,6-tetrahydro-2-pyridinone

Suppliers and Price of 1-(2-methylallyl)-4-(phenylthio)-6-(E-1-propenyl)-1,2,5,6-tetrahydro-2-pyridinone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1-(2-methylallyl)-4-(phenylthio)-6-(E-1-propenyl)-1,2,5,6-tetrahydro-2-pyridinone

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1-(2-methylallyl)-4-(phenylthio)-6-(E-1-propenyl)-1,2,5,6-tetrahydro-2-pyridinone

There total 3 articles about 1-(2-methylallyl)-4-(phenylthio)-6-(E-1-propenyl)-1,2,5,6-tetrahydro-2-pyridinone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 54.0%

: 1458-98-6
2-methyl-3-bromo-1-propene

: 1415683-61-2
4-(phenylthio)-6-(E-1-propenyl)-1,2,5,6-tetrahydro-2-pyridinone

: 1415683-63-4
1-(2-methylallyl)-4-(phenylthio)-6-(E-1-propenyl)-1,2,5,6-tetrahydro-2-pyridinone

Guidance literature:: 4-(phenylthio)-6-(E-1-propenyl)-1,2,5,6-tetrahydro-2-pyridinone; With N,N,N,N,N,N-hexamethylphosphoric triamide; n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃;

2-methyl-3-bromo-1-propene; In tetrahydrofuran; hexane; at -78 - 20 ℃;
DOI:10.1016/j.tet.2012.10.026

Reference yield:

: 597556-89-3
6-allyl-4-(phenylthio)-1-(4-toluenesulfonyl)-1,2,5,6-tetrahydropyridin-2-one

: 1415683-63-4
1-(2-methylallyl)-4-(phenylthio)-6-(E-1-propenyl)-1,2,5,6-tetrahydro-2-pyridinone

Guidance literature:: Multi-step reaction with 3 steps

1.1: Grubbs catalyst first generation / toluene / 10 h / Reflux

2.1: tri-n-butyl-tin hydride; 2,2'-azobis(isobutyronitrile) / toluene / 2 h / Reflux

3.1: n-butyllithium; N,N,N,N,N,N-hexamethylphosphoric triamide / hexane; tetrahydrofuran / -78 °C

3.2: -78 - 20 °C

With Grubbs catalyst first generation; N,N,N,N,N,N-hexamethylphosphoric triamide; n-butyllithium; 2,2'-azobis(isobutyronitrile); tri-n-butyl-tin hydride; In tetrahydrofuran; hexane; toluene;
DOI:10.1016/j.tet.2012.10.026

Reference yield:

: 1415683-60-1
4-(phenylthio)-6-(E-1-propenyl)-1-(4-toluenesulfonyl)-1,2,5,6-tetrahydro-2-pyridinone

: 1415683-63-4
1-(2-methylallyl)-4-(phenylthio)-6-(E-1-propenyl)-1,2,5,6-tetrahydro-2-pyridinone

Guidance literature:: Multi-step reaction with 2 steps

1.1: tri-n-butyl-tin hydride; 2,2'-azobis(isobutyronitrile) / toluene / 2 h / Reflux

2.1: n-butyllithium; N,N,N,N,N,N-hexamethylphosphoric triamide / hexane; tetrahydrofuran / -78 °C

2.2: -78 - 20 °C

With N,N,N,N,N,N-hexamethylphosphoric triamide; n-butyllithium; 2,2'-azobis(isobutyronitrile); tri-n-butyl-tin hydride; In tetrahydrofuran; hexane; toluene;
DOI:10.1016/j.tet.2012.10.026