Technology Process of Fmoc-Phe-Lys(Mtt)-PABOH
There total 8 articles about Fmoc-Phe-Lys(Mtt)-PABOH which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Fmoc-Lys(Mtt)-PABOH;
With
piperidine;
In
N,N-dimethyl-formamide;
for 0.166667h;
N-Fmoc L-Phe;
- Guidance literature:
-
With
N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate;
In
N,N-dimethyl-formamide;
for 0.5h;
DOI:10.1016/j.bmc.2015.09.050
- Guidance literature:
-
Multi-step reaction with 2 steps
1: O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide
2: piperidine / N,N-dimethyl-formamide
With
piperidine; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine;
In
N,N-dimethyl-formamide;
DOI:10.1039/c2sc21777e
