N-(4-aminobutyl)-1-(4-methoxyphenyl)-9H-β-carboline-3-amide

Base Information

• Chemical Name: N-(4-aminobutyl)-1-(4-methoxyphenyl)-9H-β-carboline-3-amide
• CAS No.: 1401863-92-0
• Molecular Formula: C₂₃H₂₄N₄O₂
• Molecular Weight: 388.469
• Mol file: 1401863-92-0.mol

Synonyms:N-(4-aminobutyl)-1-(4-methoxyphenyl)-9H-β-carboline-3-amide

Chemical Property of N-(4-aminobutyl)-1-(4-methoxyphenyl)-9H-β-carboline-3-amide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-(4-aminobutyl)-1-(4-methoxyphenyl)-9H-β-carboline-3-amide

There total 5 articles about N-(4-aminobutyl)-1-(4-methoxyphenyl)-9H-β-carboline-3-amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-methoxy-benzaldehyde (123-11-5) → N-(4-aminobutyl)-1-(4-methoxyphenyl)-9H-β-carboline-3-amide (1401863-92-0)

Guidance literature:

Multi-step reaction with 4 steps

1.1: acetic acid / 2 h / Reflux

1.2: pH 5

2.1: sulfuric acid / 48 h / Reflux

3.1: sulfur / xylene / 15 h / 0 °C / Reflux

4.1: dichloromethane / 22 h / 20 °C

With sulfuric acid; sulfur; acetic acid; In dichloromethane; xylene;

Reference yield:

L-tryptophan methyl ester (4299-70-1) → N-(4-aminobutyl)-1-(4-methoxyphenyl)-9H-β-carboline-3-amide (1401863-92-0)

Guidance literature:

Multi-step reaction with 3 steps

1.1: 15 h / Reflux

1.2: pH ~ 7

2.1: sulfur / xylene / 15 h / 0 °C / Reflux

3.1: dichloromethane / 22 h / 20 °C

With sulfur; In dichloromethane; xylene;

Reference yield:

(3S)-1-(4-methoxyphenyl)-1,2,3,4-tetrahydro-β-carboline-3-carboxylic acid methyl ester (243842-55-9) → N-(4-aminobutyl)-1-(4-methoxyphenyl)-9H-β-carboline-3-amide (1401863-92-0)

Guidance literature:

Multi-step reaction with 2 steps

1: sulfur / xylene / 15 h / 0 °C / Reflux

2: dichloromethane / 22 h / 20 °C

With sulfur; In dichloromethane; xylene;

upstream raw materials:

L-tryptophan methyl ester

4-methoxy-benzaldehyde

(3S)-1-(4-methoxyphenyl)-1,2,3,4-tetrahydro-β-carboline-3-carboxylic acid methyl ester

methyl 1-(4-methoxyphenyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylate

Downstream raw materials:

C₂₃H₂₄N₄O₂*ClH