2-{N'-[1-Phenyl-eth-(Z)-ylidene]-hydrazino}-thiazole-4-carboxylic acid

Base Information

• Chemical Name: 2-{N'-[1-Phenyl-eth-(Z)-ylidene]-hydrazino}-thiazole-4-carboxylic acid
• CAS No.: 136265-72-0
• Molecular Formula: C₁₂H₁₁N₃O₂S
• Molecular Weight: 261.304
• Mol file: 136265-72-0.mol

Synonyms:2-{N'-[1-Phenyl-eth-(Z)-ylidene]-hydrazino}-thiazole-4-carboxylic acid

Chemical Property of 2-{N'-[1-Phenyl-eth-(Z)-ylidene]-hydrazino}-thiazole-4-carboxylic acid

Chemical Property:

Purity/Quality:

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Technology Process of 2-{N'-[1-Phenyl-eth-(Z)-ylidene]-hydrazino}-thiazole-4-carboxylic acid

There total 1 articles about 2-{N'-[1-Phenyl-eth-(Z)-ylidene]-hydrazino}-thiazole-4-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

2-amino-5-carboxy-1,3,4-thiadiazine hydrochloride (1171535-57-1) + acetophenone (98-86-2) → 2-{N'-[1-Phenyl-eth-(Z)-ylidene]-hydrazino}-thiazole-4-carboxylic acid (136265-72-0)

Guidance literature:

With hydrogenchloride; In ethanol; water; Heating;

DOI:10.1007/BF00480848

Reference yield: 54.0%

2-{N'-[1-Phenyl-eth-(Z)-ylidene]-hydrazino}-thiazole-4-carboxylic acid (136265-72-0) → 1-(1-phenyl)ethylidenehydrazino-4-carboxy-5-bromothiazole

Guidance literature:

With bromine; In acetic acid; for 1h;

DOI:10.1007/BF00531672

upstream raw materials:

2-amino-5-carboxy-1,3,4-thiadiazine hydrochloride

acetophenone