C₂₃H₃₂N₂O₈S₂

Base Information

• Chemical Name: C₂₃H₃₂N₂O₈S₂
• CAS No.: 914982-50-6
• Molecular Formula: C₂₃H₃₂N₂O₈S₂
• Molecular Weight: 528.648
• Mol file: 914982-50-6.mol

Synonyms:C₂₃H₃₂N₂O₈S₂

Chemical Property of C₂₃H₃₂N₂O₈S₂

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₃H₃₂N₂O₈S₂

There total 7 articles about C₂₃H₃₂N₂O₈S₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

(S)-2-benzyloxy-1-((4R,5R)-5-((S)-2-benzyloxy-1-(tosylamino)ethyl)-2,2-dimethyl-1,3-dioxolan-4-yl)-N-tosylethanamine (914982-45-9) → C23H32N2O8S2 (914982-50-6)

Guidance literature:

With hydrogen; palladium on activated charcoal; In methanol; at 20 ℃; for 12h; atmospheric pressure;

DOI:10.1016/j.tet.2006.08.035

Reference yield:

1,3:4,6-di-O-benzylidene-D-mannitol (61490-28-6) → C23H32N2O8S2 (914982-50-6)

Guidance literature:

Multi-step reaction with 7 steps

1: 82 percent / Et₃N / CH₂Cl₂ / 2 h / 0 °C

2: 78 percent / BF₃*Et₂O; Et₃SiH / CH₂Cl₂ / 1 h

3: 80 percent / pTSA / acetone / 5 h / 20 °C

4: 91 percent / sodium azide / dimethylformamide / 24 h / 110 °C

5: 95 percent / hydrogen / Lindlar's catalyst / methanol / 4 h / 28 °C / 760 Torr

6: 86 percent / pyridine / 3 h / 0 - 20 °C

7: 90 percent / hydrogen / Pd/C / methanol / 12 h / 20 °C / atmospheric pressure

With pyridine; triethylsilane; sodium azide; boron trifluoride diethyl etherate; hydrogen; toluene-4-sulfonic acid; triethylamine; palladium on activated charcoal; Lindlar's catalyst; In methanol; dichloromethane; N,N-dimethyl-formamide; acetone;

DOI:10.1016/j.tet.2006.08.035

Reference yield:

mannitol (69-65-8) → C23H32N2O8S2 (914982-50-6)

Guidance literature:

Multi-step reaction with 8 steps

1: 86 percent / H₂SO₄ / dimethylformamide / 120 h / 20 °C

2: 82 percent / Et₃N / CH₂Cl₂ / 2 h / 0 °C

3: 78 percent / BF₃*Et₂O; Et₃SiH / CH₂Cl₂ / 1 h

4: 80 percent / pTSA / acetone / 5 h / 20 °C

5: 91 percent / sodium azide / dimethylformamide / 24 h / 110 °C

6: 95 percent / hydrogen / Lindlar's catalyst / methanol / 4 h / 28 °C / 760 Torr

7: 86 percent / pyridine / 3 h / 0 - 20 °C

8: 90 percent / hydrogen / Pd/C / methanol / 12 h / 20 °C / atmospheric pressure

With pyridine; triethylsilane; sodium azide; sulfuric acid; boron trifluoride diethyl etherate; hydrogen; toluene-4-sulfonic acid; triethylamine; palladium on activated charcoal; Lindlar's catalyst; In methanol; dichloromethane; N,N-dimethyl-formamide; acetone;

DOI:10.1016/j.tet.2006.08.035

upstream raw materials:

(S)-2-benzyloxy-1-((4R,5R)-5-((S)-2-benzyloxy-1-(tosylamino)ethyl)-2,2-dimethyl-1,3-dioxolan-4-yl)-N-tosylethanamine

1,3:4,6-di-O-benzylidene-D-mannitol

mannitol

2,5-Di-O-mesyl-1,3:4,6-di-O-benzylidene-D-mannitol

Downstream raw materials:

Methanesulfonic acid (S)-2-{(4R,5R)-5-[(S)-2-methanesulfonyloxy-1-(toluene-4-sulfonylamino)-ethyl]-2,2-dimethyl-[1,3]dioxolan-4-yl}-2-(toluene-4-sulfonylamino)-ethyl ester

(S)-2-((4R,5R)-2,2-dimethyl-5-((S)-1-tosylaziridin-2-yl)-1,3-dioxolan-4-yl)-1-tosyl-aziridine