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Mannitol

Base Information Edit
  • Chemical Name:Mannitol
  • CAS No.:69-65-8
  • Deprecated CAS:123897-58-5,75398-80-0,85085-15-0,1081757-07-4,133-43-7,36413-61-3,5149-40-6,85085-15-0
  • Molecular Formula:C6H14O6
  • Molecular Weight:182.174
  • Hs Code.:29054300
  • European Community (EC) Number:200-711-8,201-770-2
  • UNII:3OWL53L36A
  • DSSTox Substance ID:DTXSID1023235,DTXSID30858955
  • Nikkaji Number:J2.369H
  • Wikipedia:Mannitol
  • Wikidata:Q407646
  • NCI Thesaurus Code:C625
  • RXCUI:6628
  • Metabolomics Workbench ID:37414
  • ChEMBL ID:CHEMBL689
  • Mol file:69-65-8.mol
Mannitol

Synonyms:(L)-Mannitol;Mannitol;Osmitrol;Osmofundin

Suppliers and Price of Mannitol
Supply Marketing:Edit
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • Usbiological
  • D-Mannitol
  • 1Kg
  • $ 106.00
  • TRC
  • D-Mannitol-d8
  • 50mg
  • $ 1455.00
  • TRC
  • D-Mannitol-d8
  • 5mg
  • $ 185.00
  • TCI Chemical
  • D-Mannitol
  • 25G
  • $ 17.00
  • TCI Chemical
  • D-Mannitol
  • 500G
  • $ 33.00
  • Sigma-Aldrich
  • Parteck Delta M (Mannitol) EMPROVE? ESSENTIAL Ph Eur,BP,USP,JP,E 421
  • 1 kg
  • $ 130.00
  • Sigma-Aldrich
  • Parteck Delta M (Mannitol) EMPROVE ESSENTIAL Ph Eur,BP,USP,JP,E 421
  • 1126351000
  • $ 130.00
  • Sigma-Aldrich
  • D(-)Mannitol - CAS 69-65-8 - Calbiochem
  • 500gm
  • $ 126.00
  • Sigma-Aldrich
  • D(-)Mannitol - CAS 69-65-8 - Calbiochem
  • 500 g
  • $ 124.87
  • Sigma-Aldrich
  • D-Mannitol EMPROVE? ESSENTIAL Ph Eur,BP,USP,JP,FCC,E 421
  • 2.5 kg
  • $ 112.00
Total 227 raw suppliers
Chemical Property of Mannitol Edit
Chemical Property:
  • Appearance/Colour:White crystalline powder 
  • Vapor Pressure:7.22E-12mmHg at 25°C 
  • Melting Point:167-170 °C(lit.) 
  • Refractive Index:1.597 
  • Boiling Point:494.865 °C at 760 mmHg 
  • PKA:13.5(at 18℃) 
  • Flash Point:292.497 °C 
  • PSA:121.38000 
  • Density:1.596 g/cm3 
  • LogP:-3.58540 
  • Storage Temp.:Store at RT. 
  • Solubility.:H2O: 1 M at 20 °C, clear, colorless 
  • Water Solubility.:soluble 
  • XLogP3:-3.1
  • Hydrogen Bond Donor Count:6
  • Hydrogen Bond Acceptor Count:6
  • Rotatable Bond Count:5
  • Exact Mass:182.07903816
  • Heavy Atom Count:12
  • Complexity:105
Purity/Quality:

99.5% *data from raw suppliers

D-Mannitol *data from reagent suppliers

Safty Information:
  • Pictogram(s): IrritantXi 
  • Hazard Codes:Xi 
  • Statements: 36/37/38 
  • Safety Statements: 24/25-36-26 
MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:
  • Chemical Classes:Biological Agents -> Monosaccharides and Derivatives
  • Canonical SMILES:C(C(C(C(C(CO)O)O)O)O)O
  • Isomeric SMILES:C([C@H]([C@H]([C@@H]([C@@H](CO)O)O)O)O)O
  • Recent ClinicalTrials:Efficacy of Sodium Thiosulfate and Mannitol in Reducing Ototoxicity in Adult Patients Receiving Cisplatin Chemotherapy
  • Recent EU Clinical Trials:Efficacy and Safety of mAnniTol in bowel preparation: assessment of adequacy and presence of Intestinal levelS of hydrogen and methane during elective colonoscopy aFter mAnnitol or standard split 2-liter polyethylene glycol solution plus asCorbaTe – a phase II/III, International, multicentre, randomized, parallel-group, endoscOpist-bliNded, dose-finding/non-inferiority study - SATISFACTION
  • Recent NIPH Clinical Trials:A phase 1 study in patients with Fukuyama-type congenital muscular dystrophy
  • Description A white, crystalline solid consisting of D-mannitol and a small quantity of sorbitol. It is odorless and has a sweet taste. It is soluble in water, very slightly soluble in alcohol, and practically insoluble in most other common organic solvents. It is prepared commercially by catalytic reduction of glucose. Mannitol occurs in small amounts in a variety of foods such as olives, beets, and celery, and in the exudate of certain trees.
  • Uses inhibitor of norepinephrine and seritonin uptake, treatment of fibromyalgia Labelled D-Mannitol (M165000). D-Mannitol is widespread in plants and plant exudates; obtained from manna and seaweeds. D-Mannitol is used in the food industry as anticaking and free-flow agent, flavo ring agent, lubricant and release agent, stabilizer and thickener and nutritive sweetener. Used in titrimetric determination of boric acid. Used with boric acid in the manufacture of dry electrolytic condensers for radio applications; in making artificial resins and plasticizers; in pharmacy as excipient and diluent for solids and liqs; in analytical chemistry for boron determinations; in the manufacture of mannitol hexanitrate. Used in the food industry as anticaking and free-flow agent, flavoring agent, lubricant and release agent, stabilizer and thickener and nutritive sweetener.
  • Therapeutic Function Diuretic, Diagnostic aid (kidney function)
Technology Process of Mannitol

There total 250 articles about Mannitol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
With ruthenium-carbon composite; hydrogen; ammonium tungstate; In water; at 160 ℃; for 2h; under 30003 Torr; Pressure; Temperature; Catalytic behavior; Autoclave;
DOI:10.1002/open.202100023
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