5,5’-Dihydroxylysinonorleucine

Base Information

• Chemical Name: 5,5’-Dihydroxylysinonorleucine
• CAS No.: 32619-23-1
• Molecular Formula: C₁₂H₂₅N₃O₆
• Molecular Weight: 307.347
• Mol file: 32619-23-1.mol

Synonyms:L-Lysine,N6-(5-amino-5-carboxy-2-hydroxypentyl)-5-hydroxy-, erythro-; Norleucine,6,6'-iminobis[5-hydroxy-, L- (8CI); DHLNL; Hydroxylysinohydroxynorleucine;Reduced syndesine; d,d'-Dihydroxylysinonorleucine

Chemical Property of 5,5’-Dihydroxylysinonorleucine

Chemical Property:

• PSA: 179.13000
• LogP: -0.52650
• Storage Temp.: Hygroscopic, Refrigerator, Under Inert Atmosphere
• Solubility.: Water (Slightly)

Purity/Quality:

99% ^*data from raw suppliers

(5S,5’S)-DihydroxyLysinonorleucine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Collagen reducible crosslink agent Collagen reducible crosslink agent.

Technology Process of 5,5’-Dihydroxylysinonorleucine

There total 12 articles about 5,5’-Dihydroxylysinonorleucine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

C47H51N3O6 → (2S,5R)-2-amino-6[(2S,5S)-5-amino-5-carboxy-2-hydroxypentylamino]-5-hydroxyhexanoic acid (32619-23-1,12764-49-7,869111-63-7)

Guidance literature:

With hydrogen; palladium dichloride; In tetrahydrofuran; ethanol; water;

DOI:10.1016/j.tetasy.2005.08.023

Reference yield:

C47H51N3O6 → (2S,5S)-2-amino-6[(2S,5S)-5-amino-5-carboxy-2-hydroxypentylamino]-5-hydroxyhexanoic acid (32619-23-1,12764-49-7,869111-63-7)

Guidance literature:

With hydrogen; palladium dichloride; In tetrahydrofuran; ethanol; water; for 48h; under 3102.89 Torr;

DOI:10.1016/j.tetasy.2005.08.023

Reference yield:

C47H51N3O6 → (2S,5R)-2-amino-6[(2R,5S)-5-amino-5-carboxy-2-hydroxypentylamino]-5-hydroxyhexanoic acid (32619-23-1,12764-49-7,869111-63-7)

Guidance literature:

With hydrogen; palladium dichloride; In tetrahydrofuran; ethanol; water; for 48h; under 3102.89 Torr;

DOI:10.1016/j.tetasy.2005.08.023

upstream raw materials:

tert-butyl (3S,5S,6R)-3-[(3R)-3,4-epoxybutyl]-2-oxo-5,6-diphenyl-1,4-oxazinane-4-carboxylate

tert-butyl (3S,5S,6R)-3-[(3S)-3,4-epoxybutyl]-2-oxo-5,6-diphenyl-1,4-oxazinane-4-carboxylate

tert-butyl (3S,5S,6R)-3-[(3S)-3-hydroxy-4-bromo-butyl]-2-oxo-5,6-diphenyl-1,4-oxazinane-4-carboxylate

tert-butyl (3S,5S,6R)-3-[(3R)-3-hydroxy-4-bromo-butyl]-2-oxo-5,6-diphenyl-1,4-oxazinane-4-carboxylate