[1-methoxy-2-(trimethylsilyl)vinyloxy]trimethylsilane

Base Information

• Chemical Name: [1-methoxy-2-(trimethylsilyl)vinyloxy]trimethylsilane
• CAS No.: 32583-40-7
• Molecular Formula: C9H22 O2 Si2
• Molecular Weight: 218.443
• Hs Code.: 2931900090
• Mol file: 32583-40-7.mol

Synonyms:3-Oxa-2,6-disilahept-4-ene,4-methoxy-2,2,6,6-tetramethyl- (8CI)

Chemical Property of [1-methoxy-2-(trimethylsilyl)vinyloxy]trimethylsilane

Chemical Property:

• Vapor Pressure: 1.658mmHg at 25°C
• Refractive Index: 1.421
• Boiling Point: 173.886°C at 760 mmHg
• Flash Point: 49.722°C
• PSA: 18.46000
• Density: 0.858g/cm³
• LogP: 3.20310

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 10-36/37/38
• Safety Statements: 16-26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of [1-methoxy-2-(trimethylsilyl)vinyloxy]trimethylsilane

There total 1 articles about [1-methoxy-2-(trimethylsilyl)vinyloxy]trimethylsilane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 29.0%

acetic acid methyl ester (79-20-9) + trimethylsilyl trifluoromethanesulfonate (27607-77-8) → methyl (trimethylsilyl)acetate (2916-76-9) + [[1-methoxy-2-(trimethylsilyl)ethenyl]oxy]trimethylsilane (32583-40-7) + 2,2-Bis(trimethylsilyl)ethansaeure-methylester (60989-29-9)

Guidance literature:

With triethylamine; In diethyl ether; for 2h; Yields of byproduct given; Ambient temperature;

Reference yield: 79.0%

cyclohexenone (930-68-7) + [[1-methoxy-2-(trimethylsilyl)ethenyl]oxy]trimethylsilane (32583-40-7) → 3-<(methoxycarbonyl)(trimethylsilyl)methyl>cyclohexan-1-one (72049-87-7)

Guidance literature:

With titanium tetrachloride; In dichloromethane; at -78 ℃; for 2h;

DOI:10.1021/jo01290a006

Reference yield: 40.0%

[[1-methoxy-2-(trimethylsilyl)ethenyl]oxy]trimethylsilane (32583-40-7) + C25H31NO6 → (3-methyl-butyl)-butenedioic acid 1-((3aR)-2-methoxy-(3arC4,14bc)-1,5,6,8,9,14b-hexahydro-4H-cyclopenta[b][1,3]dioxolo[4',5':4,5]benzo[1,2-d]pyrrolo[1,2-a]azepin-1t-yl) ester 4-methyl ester (54086-27-0) + deoxyharringtonine (36804-95-2)

Guidance literature:

[[1-methoxy-2-(trimethylsilyl)ethenyl]oxy]trimethylsilane; C₂₅H₃₁NO₆; With boron trifluoride diethyl etherate; In dichloromethane; at -25 ℃; for 22h;

With potassium fluoride dihydrate; In acetonitrile; at 70 ℃; for 4h; Temperature; diastereoselective reaction;

DOI:10.1021/acs.orglett.7b00743

upstream raw materials:

acetic acid methyl ester

trimethylsilyl trifluoromethanesulfonate

Downstream raw materials:

3-<(methoxycarbonyl)(trimethylsilyl)methyl>cyclohexan-1-one

(3-methyl-butyl)-butenedioic acid 1-((3aR)-2-methoxy-(3arC⁴,14bc)-1,5,6,8,9,14b-hexahydro-4H-cyclopenta[b][1,3]dioxolo[4',5':4,5]benzo[1,2-d]pyrrolo[1,2-a]azepin-1t-yl) ester 4-methyl ester

deoxyharringtonine