Technology Process of 1H-1-(1'-phenylethynyl)-5-methyl-1,2,3-benziodoxathiole 3,3-dioxide
There total 4 articles about 1H-1-(1'-phenylethynyl)-5-methyl-1,2,3-benziodoxathiole 3,3-dioxide which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
toluene-4-sulfonic acid;
In
acetonitrile;
for 7h;
Heating;
DOI:10.1021/jo00077a071
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 1.) NaNO2, conc. HCl, 2.) NaI, urea / 1.) H2O, 0-5 deg C, 30 min, 2.) H2O, 0-5 deg C, 2 h; r.t., 1 h; 50 deg C, 13 h
2: 65 percent / aq. HCl / r.t., 3 h; 50 deg C, 2 h; r.t., overnight
3: 93 percent / peroxyacetic acid / acetic acid / 1.) 15 deg C, 1 h, 2.) r.t., overnight
4: 51 percent / TsOH*H2O / acetonitrile / 7 h / Heating
With
hydrogenchloride; peracetic acid; toluene-4-sulfonic acid; urea; sodium iodide; sodium nitrite;
In
acetic acid; acetonitrile;
DOI:10.1021/jo00077a071
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 93 percent / peroxyacetic acid / acetic acid / 1.) 15 deg C, 1 h, 2.) r.t., overnight
2: 51 percent / TsOH*H2O / acetonitrile / 7 h / Heating
With
peracetic acid; toluene-4-sulfonic acid;
In
acetic acid; acetonitrile;
DOI:10.1021/jo00077a071
