(R)-3-((tert-butyldiphenylsilyl)oxy)-4-((4R,6R)-6-((S)-2-((tert-butyldiphenylsilyl)oxy)but-3-en-1-yl)-2,2-dimethyl-1,3-dioxan-4-yl)butyl pivalate

Base Information

Chemical Name:(R)-3-((tert-butyldiphenylsilyl)oxy)-4-((4R,6R)-6-((S)-2-((tert-butyldiphenylsilyl)oxy)but-3-en-1-yl)-2,2-dimethyl-1,3-dioxan-4-yl)butyl pivalate
CAS No.:1290537-67-5
Molecular Formula:C₅₁H₇₀O₆Si₂
Molecular Weight:835.284
Hs Code.:

Synonyms:(R)-3-((tert-butyldiphenylsilyl)oxy)-4-((4R,6R)-6-((S)-2-((tert-butyldiphenylsilyl)oxy)but-3-en-1-yl)-2,2-dimethyl-1,3-dioxan-4-yl)butyl pivalate

Suppliers and Price of (R)-3-((tert-butyldiphenylsilyl)oxy)-4-((4R,6R)-6-((S)-2-((tert-butyldiphenylsilyl)oxy)but-3-en-1-yl)-2,2-dimethyl-1,3-dioxan-4-yl)butyl pivalate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (R)-3-((tert-butyldiphenylsilyl)oxy)-4-((4R,6R)-6-((S)-2-((tert-butyldiphenylsilyl)oxy)but-3-en-1-yl)-2,2-dimethyl-1,3-dioxan-4-yl)butyl pivalate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (R)-3-((tert-butyldiphenylsilyl)oxy)-4-((4R,6R)-6-((S)-2-((tert-butyldiphenylsilyl)oxy)but-3-en-1-yl)-2,2-dimethyl-1,3-dioxan-4-yl)butyl pivalate

There total 6 articles about (R)-3-((tert-butyldiphenylsilyl)oxy)-4-((4R,6R)-6-((S)-2-((tert-butyldiphenylsilyl)oxy)but-3-en-1-yl)-2,2-dimethyl-1,3-dioxan-4-yl)butyl pivalate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 1290537-66-4
(R)-3-((tert-butyldiphenylsilyl)oxy)-4-((4R,6R)-6-((S)-2-((tert-butyldiphenylsilyl)oxy)-4-((2-nitrophenyl)selanyl)butyl)-2,2-dimethyl-1,3-dioxan-4-yl)butyl pivalate

: 1290537-67-5
(R)-3-((tert-butyldiphenylsilyl)oxy)-4-((4R,6R)-6-((S)-2-((tert-butyldiphenylsilyl)oxy)but-3-en-1-yl)-2,2-dimethyl-1,3-dioxan-4-yl)butyl pivalate

Guidance literature:: With dihydrogen peroxide; sodium hydrogencarbonate; In tetrahydrofuran; water; at 25 ℃; for 12h; Inert atmosphere;
DOI:10.1021/ol200735r

Reference yield:

: 1182723-08-5
(2R,2'R)-1,1'-((4S,6S)-dimethyl-1,3-dioxane-4,6-diyl)dipent-4-en-2-ol

: 1290537-67-5
(R)-3-((tert-butyldiphenylsilyl)oxy)-4-((4R,6R)-6-((S)-2-((tert-butyldiphenylsilyl)oxy)but-3-en-1-yl)-2,2-dimethyl-1,3-dioxan-4-yl)butyl pivalate

Guidance literature:: Multi-step reaction with 6 steps

1: 1H-imidazole / dichloromethane / 18 h / 25 °C / Inert atmosphere

2: ozone / methanol; dichloromethane / -78 °C / Inert atmosphere

3: sodium tetrahydroborate / methanol; dichloromethane / 14 h / -78 - 25 °C / Inert atmosphere

4: pyridine / dichloromethane / 0 - 25 °C / Inert atmosphere

5: tributylphosphine / tetrahydrofuran / 12 h / 25 °C / Inert atmosphere

6: dihydrogen peroxide; sodium hydrogencarbonate / tetrahydrofuran; water / 12 h / 25 °C / Inert atmosphere

With pyridine; 1H-imidazole; sodium tetrahydroborate; tributylphosphine; dihydrogen peroxide; sodium hydrogencarbonate; ozone; In tetrahydrofuran; methanol; dichloromethane; water;
DOI:10.1021/ol200735r

Reference yield:

: 1290537-62-0
(((2R,2'R)-((4R,6R)-2,2-dimethyl-1,3-dioxane-4,6-diyl)bis(pent-4-ene-2,1-diyl))bis(oxy))bis(tertbutyldiphenylsilane)

: 1290537-67-5
(R)-3-((tert-butyldiphenylsilyl)oxy)-4-((4R,6R)-6-((S)-2-((tert-butyldiphenylsilyl)oxy)but-3-en-1-yl)-2,2-dimethyl-1,3-dioxan-4-yl)butyl pivalate

Guidance literature:: Multi-step reaction with 5 steps

1: ozone / methanol; dichloromethane / -78 °C / Inert atmosphere

2: sodium tetrahydroborate / methanol; dichloromethane / 14 h / -78 - 25 °C / Inert atmosphere

3: pyridine / dichloromethane / 0 - 25 °C / Inert atmosphere

4: tributylphosphine / tetrahydrofuran / 12 h / 25 °C / Inert atmosphere

5: dihydrogen peroxide; sodium hydrogencarbonate / tetrahydrofuran; water / 12 h / 25 °C / Inert atmosphere

With pyridine; sodium tetrahydroborate; tributylphosphine; dihydrogen peroxide; sodium hydrogencarbonate; ozone; In tetrahydrofuran; methanol; dichloromethane; water;
DOI:10.1021/ol200735r