(2,3-Dihydrobenzo[B][1,4]dioxin-2-YL)(4-(2-hydroxyethyl)piperazin-1-YL) methanone

Base Information

Chemical Name:(2,3-Dihydrobenzo[B][1,4]dioxin-2-YL)(4-(2-hydroxyethyl)piperazin-1-YL) methanone
CAS No.:219851-02-2
Molecular Formula:C₁₅H₂₀N₂O₄
Molecular Weight:292.335
Hs Code.:
DSSTox Substance ID:DTXSID10441864
Nikkaji Number:J1.082.668C
Mol file:219851-02-2.mol

Synonyms:219851-02-2;(2,3-DIHYDROBENZO[B][1,4]DIOXIN-2-YL)(4-(2-HYDROXYETHYL)PIPERAZIN-1-YL) METHANONE;2,3-dihydro-1,4-benzodioxin-3-yl-[4-(2-hydroxyethyl)piperazin-1-yl]methanone;(2,3-Dihydrobenzo[b][1,4]dioxin-2-yl)(4-(2-hydroxyethyl)piperazin-1-yl)methanone;SCHEMBL7978591;DTXSID10441864;AKOS008976748;4-(2,3-Dihydro-1,4-benzodioxin-2-ylcarbonyl)piperazine-1-ethanol;(2,3-Dihydro-1,4-benzodioxin-2-yl)[4-(2-hydroxyethyl)piperazin-1-yl]methanone;(2,3-Dihydrobenzo[b][1,4]dioxin-3-yl)(4-(2-hydroxyethyl)piperazin-1-yl)methanone

Suppliers and Price of (2,3-Dihydrobenzo[B][1,4]dioxin-2-YL)(4-(2-hydroxyethyl)piperazin-1-YL) methanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 1 raw suppliers

Chemical Property of (2,3-Dihydrobenzo[B][1,4]dioxin-2-YL)(4-(2-hydroxyethyl)piperazin-1-YL) methanone

Chemical Property:

PSA：62.24000
LogP:-0.16130
XLogP3:0.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:292.14230712
Heavy Atom Count:21
Complexity:358

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN(CCN1CCO)C(=O)C2COC3=CC=CC=C3O2

Technology Process of (2,3-Dihydrobenzo[B][1,4]dioxin-2-YL)(4-(2-hydroxyethyl)piperazin-1-YL) methanone

There total 3 articles about (2,3-Dihydrobenzo[B][1,4]dioxin-2-YL)(4-(2-hydroxyethyl)piperazin-1-YL) methanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 103-76-4
1-(2-hydroxyethyl)piperazine

: 4739-94-0
ethyl 2,3-dihydro-1,4-benzodioxin-2-carboxylate

: 219851-02-2
N-(2,3-dihydrobenzo<1,4>dioxin-2-carbonyl)-N'-(2-hydroxyethyl)piperazine

Guidance literature:: at 110 ℃; for 3h;
DOI:10.1021/jo980830j

Reference yield: 98.0%

: 219851-02-2
N-(2,3-dihydrobenzo<1,4>dioxin-2-carbonyl)-N'-(2-hydroxyethyl)piperazine

Guidance literature:

Reference yield: 92.0%

: 103-76-4
1-(2-hydroxyethyl)piperazine

: 3663-80-7,34385-93-8,70918-53-5,70918-54-6
1,4-benzodioxane-2-carboxylic acid

: 219851-02-2
N-(2,3-dihydrobenzo<1,4>dioxin-2-carbonyl)-N'-(2-hydroxyethyl)piperazine

Guidance literature:: With 4-methyl-morpholine; 2-chloro-4,6-dimethoxy-1 ,3,5-triazine; In dichloromethane; at 20 ℃; for 0.166667h;
DOI:10.1016/S0040-4039(03)00684-1