12-bromo-N-[(1R,2R)-1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl]dodecanamide

Base Information

• Chemical Name: 12-bromo-N-[(1R,2R)-1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl]dodecanamide
• CAS No.: 1136681-28-1
• Molecular Formula: C₂₁H₃₃BrN₂O₅
• Molecular Weight: 473.407

Synonyms:12-bromo-N-[(1R,2R)-1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl]dodecanamide

Chemical Property of 12-bromo-N-[(1R,2R)-1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl]dodecanamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 12-bromo-N-[(1R,2R)-1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl]dodecanamide

There total 2 articles about 12-bromo-N-[(1R,2R)-1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl]dodecanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

12-bromododecanoic acid (73367-80-3) + (1R,2R)-2-Amino-1-(4-nitrophenyl)-1,3-propanediol (119-62-0,716-61-0,2792-51-0,2792-52-1,2964-48-9,3689-55-2,63526-31-8,71115-69-0,140694-64-0) → 12-bromo-N-[(1R,2R)-1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl]dodecanamide (1136681-28-1)

Guidance literature:

12-bromododecanoic acid; With 1-chloro-1-(dimethylamino)-2-methyl-1-propene; In tetrahydrofuran; at 0 - 20 ℃; for 0.666667h;

(1R,2R)-2-Amino-1-(4-nitrophenyl)-1,3-propanediol; With sodium acetate; In tetrahydrofuran; water; at 20 ℃; for 2.5h;

Reference yield: 78.0%

(1R,2R)-2-Amino-1-(4-nitrophenyl)-1,3-propanediol (119-62-0,716-61-0,2792-51-0,2792-52-1,2964-48-9,3689-55-2,63526-31-8,71115-69-0,140694-64-0) + 12-bromododecanoyl chloride (61658-00-2) → 12-bromo-N-[(1R,2R)-1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl]dodecanamide (1136681-28-1)

Guidance literature:

With sodium acetate; In tetrahydrofuran; water; at 20 ℃; for 0.516667h;

DOI:10.1016/j.bmc.2009.01.057

Reference yield: 95.0%

12-bromo-N-[(1R,2R)-1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl]dodecanamide (1136681-28-1) + dimethyl amine (124-40-3) → (1R,2R)-2-N-(12'-(N,N-dimethylamino)dodecanoylamino)-1-(4''-nitrophenyl)-1,3-propandiol (1136681-32-7)

Guidance literature:

With sodium hydroxide; In tetrahydrofuran; at 20 ℃;

DOI:10.1016/j.bmc.2009.01.057

upstream raw materials:

(1R,2R)-2-Amino-1-(4-nitrophenyl)-1,3-propanediol

12-bromododecanoyl chloride

12-bromododecanoic acid

Downstream raw materials:

(1R,2R)-2-N-[12'-(imidazol-1-yl)dodecanoylamino]-1-(4'''-nitrophenyl)-1,3-propandiol

(1R,2R)-2-N-(12'-aminododecanoylamino)-1-(4''-nitrophenyl)-1,3-propandiol

(1R,2R)-2-N-(12'-(N,N-dimethylamino)dodecanoylamino)-1-(4''-nitrophenyl)-1,3-propandiol

(1R,2R)-2-N-(12'-(N-methylamino)dodecanoylamino)-1-(4''-nitrophenyl)-1,3-propandiol

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 1136681-28-1 12-bromo-N-[(1R,2R)-1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl]dodecanamide

Send

Send

Metric Ton KG G Pound L ML

Send

Send