2-hydroxy-4-methoxymethoxy-6-prenyloxyacetophenone

Base Information

• Chemical Name: 2-hydroxy-4-methoxymethoxy-6-prenyloxyacetophenone
• CAS No.: 450336-12-6
• Molecular Formula: C₁₅H₂₀O₅
• Molecular Weight: 280.321
• Mol file: 450336-12-6.mol

Synonyms:2-hydroxy-4-methoxymethoxy-6-prenyloxyacetophenone

Chemical Property of 2-hydroxy-4-methoxymethoxy-6-prenyloxyacetophenone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of 2-hydroxy-4-methoxymethoxy-6-prenyloxyacetophenone

There total 2 articles about 2-hydroxy-4-methoxymethoxy-6-prenyloxyacetophenone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

2'-hydroxy-4',6'-bis(methoxymethoxy)acetophenone (65490-09-7) + prenyl bromide (870-63-3) → 2-hydroxy-4-methoxymethoxy-6-prenyloxyacetophenone (450336-12-6)

Guidance literature:

2'-hydroxy-4',6'-bis(methoxymethoxy)acetophenone; prenyl bromide; With potassium carbonate; In acetone; for 4h; Heating;

With silica gel; flash column chromatography;

DOI:10.1081/SCC-120003156

Reference yield: 68.0%

1-{2,4-bis(methoxymethoxy)-6-[(3-methylbut-2-en-1-yl)oxy]phenyl}ethanone (160624-22-6) → 2-hydroxy-4-methoxymethoxy-6-prenyloxyacetophenone (450336-12-6)

Guidance literature:

With hydrogenchloride; In water; acetone; for 4h; pH=2; Cooling with ice;

DOI:10.1021/np800188b

Reference yield: 90.0%

2-hydroxy-4-methoxymethoxy-6-prenyloxyacetophenone (450336-12-6) → 1-(2,6-dihydroxy-4-(methoxymethoxy)-3-(3-methylbut-2-en-1-yl)phenyl)ethanone (450336-13-7)

Guidance literature:

With N,N-dimethyl-aniline; for 4.5h; Heating;

DOI:10.1081/SCC-120003156

upstream raw materials:

2'-hydroxy-4',6'-bis(methoxymethoxy)acetophenone

prenyl bromide

1-{2,4-bis(methoxymethoxy)-6-[(3-methylbut-2-en-1-yl)oxy]phenyl}ethanone

Downstream raw materials:

1-(2,6-dihydroxy-4-(methoxymethoxy)-3-(3-methylbut-2-en-1-yl)phenyl)ethanone

isoevodionol

C₂₀H₂₈O₅