2,2-Dimethyl-6-acetyl-7-methoxy-2H-1-benzopyran-5-ol

Base Information

• Chemical Name: 2,2-Dimethyl-6-acetyl-7-methoxy-2H-1-benzopyran-5-ol
• CAS No.: 25983-76-0
• Molecular Formula: C14H16 O4
• Molecular Weight: 248.27
• Hs Code.: 2914509090
• Mol file: 25983-76-0.mol

Synonyms:Ketone,5-hydroxy-7-methoxy-2,2-dimethyl-2H-1-benzopyran-6-yl methyl (8CI);2,2-Dimethyl-5-hydroxy-6-acetyl-7-methoxychromene; Isoevodionol

Chemical Property of 2,2-Dimethyl-6-acetyl-7-methoxy-2H-1-benzopyran-5-ol

Chemical Property:

• PSA: 55.76000
• LogP: 2.78760

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2,2-Dimethyl-6-acetyl-7-methoxy-2H-1-benzopyran-5-ol

There total 20 articles about 2,2-Dimethyl-6-acetyl-7-methoxy-2H-1-benzopyran-5-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

3,3-dimethyl acrylaldehyde (107-86-8) + 4,6-dihydroxy-2-methoxyacetophenone (3602-54-8) → isoevodionol (25983-76-0)

Guidance literature:

With ethylenediamine diacetic acid; In toluene; for 12h; Heating;

DOI:10.3390/12071420

Reference yield: 90.0%

1-[2,4-dihydroxy-6-methoxy-3-(3-methylbut-2-enyl)phenyl]ethanone (30403-01-1) → isoevodionol (25983-76-0)

Guidance literature:

With 2,3-dicyano-5,6-dichloro-p-benzoquinone; In 1,4-dioxane; benzene; for 3h; Reflux;

DOI:10.1021/np800188b

Reference yield: 84.0%

2,3-dihydro-5-hydroxy-7-methoxy-2,2-dimethyl-4H-1-benzopyran-4-one (1019-60-9) + acetyl chloride (75-36-5) → isoevodionol (25983-76-0)

Guidance literature:

2,3-dihydro-5-hydroxy-7-methoxy-2,2-dimethyl-4H-1-benzopyran-4-one; acetyl chloride;

With 2,3-dicyano-5,6-dichloro-p-benzoquinone; Further stages.;

DOI:10.1002/jccs.200700119

upstream raw materials:

dimethylacetal of 3-methyl-3-hydroxybutyraldehyde

4,6-dihydroxy-2-methoxyacetophenone

6-Acetyl-5-hydroxy-7-methoxy-3,4-dihydro-2,2-dimethyl-2H<1>benzopyran

1-[2,4-dihydroxy-6-methoxy-3-(3-methylbut-2-enyl)phenyl]ethanone

Downstream raw materials:

1,3-dioxo-1-(5-hydroxy-7-methoxy-2,2-dimethyl-2H-1-benzopyran-6-yl)-3-(2',4'-dimethoxy-phenyl)-propane

6-O-acetyl-2,2-dimethyl-5-(4'-methoxy-benzoyloxy)-2H-benzopyran

Alloptaeroxylin methyl ether

(2E)-1-(5-hydroxy-7-methoxy-2,2-dimethyl-2H-chromen-6-yl)-3-(4-methoxyphenyl)prop-2-en-1-one