1,2-O-isopropylidene-3-O-(m-nitrobenzenesulfonyl)-4-O-pivaloyl-L-threitol

Base Information

• Chemical Name: 1,2-O-isopropylidene-3-O-(m-nitrobenzenesulfonyl)-4-O-pivaloyl-L-threitol
• CAS No.: 132842-19-4
• Molecular Formula: C₁₈H₂₅NO₉S
• Molecular Weight: 431.464
• Mol file: 132842-19-4.mol

Synonyms:1,2-O-isopropylidene-3-O-(m-nitrobenzenesulfonyl)-4-O-pivaloyl-L-threitol

Chemical Property of 1,2-O-isopropylidene-3-O-(m-nitrobenzenesulfonyl)-4-O-pivaloyl-L-threitol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,2-O-isopropylidene-3-O-(m-nitrobenzenesulfonyl)-4-O-pivaloyl-L-threitol

There total 4 articles about 1,2-O-isopropylidene-3-O-(m-nitrobenzenesulfonyl)-4-O-pivaloyl-L-threitol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

(2S)-2-[(1S)-3,3-dimethyl(2,4-dioxolanyl)]-2-hydroxyethyl 2,2-dimethylpropanoate (119927-19-4) + 3-nitrobenzenesulphonyl chloride (121-51-7) → 1,2-O-isopropylidene-3-O-(m-nitrobenzenesulfonyl)-4-O-pivaloyl-L-threitol (132842-19-4)

Guidance literature:

With pyridine; dmap; In dichloromethane; for 24h; Ambient temperature;

DOI:10.1039/P19940002849

Reference yield:

(2S,3S)-1,2-O-isopropylidene-1,2,3,4-tetrol (91274-05-4) → 1,2-O-isopropylidene-3-O-(m-nitrobenzenesulfonyl)-4-O-pivaloyl-L-threitol (132842-19-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 77 percent / pyridine / CH₂Cl₂ / 2 h / Ambient temperature

2: 100 percent / DMAP, pyridine / CH₂Cl₂ / 24 h / Ambient temperature

With pyridine; dmap; In dichloromethane;

DOI:10.1039/P19940002849

Reference yield:

pivaloyl chloride (3282-30-2) → 1,2-O-isopropylidene-3-O-(m-nitrobenzenesulfonyl)-4-O-pivaloyl-L-threitol (132842-19-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 77 percent / pyridine / CH₂Cl₂ / 2 h / Ambient temperature

2: 100 percent / DMAP, pyridine / CH₂Cl₂ / 24 h / Ambient temperature

With pyridine; dmap; In dichloromethane;

DOI:10.1039/P19940002849

upstream raw materials:

(2S)-2-[(1S)-3,3-dimethyl(2,4-dioxolanyl)]-2-hydroxyethyl 2,2-dimethylpropanoate

3-nitrobenzenesulphonyl chloride

(2S,3S)-1,2-O-isopropylidene-1,2,3,4-tetrol

pivaloyl chloride

Downstream raw materials:

(2S,3R)-3,4-epoxy-1,2-O-isopropylidenebutane-1,2-diol