4-({6-[4-(2,2,2-trifluoroethoxy)phenyl]pyridin-3-yl}sulfonyl)tetrahydro-2H-pyran-4-carboxylic acid trifluoroacetate

Base Information

Chemical Name:4-({6-[4-(2,2,2-trifluoroethoxy)phenyl]pyridin-3-yl}sulfonyl)tetrahydro-2H-pyran-4-carboxylic acid trifluoroacetate
CAS No.:701270-61-3
Molecular Formula:C₂HF₃O₂*C₁₉H₁₈F₃NO₆S
Molecular Weight:559.44
Hs Code.:

Synonyms:4-({6-[4-(2,2,2-trifluoroethoxy)phenyl]pyridin-3-yl}sulfonyl)tetrahydro-2H-pyran-4-carboxylic acid trifluoroacetate

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Chemical Property of 4-({6-[4-(2,2,2-trifluoroethoxy)phenyl]pyridin-3-yl}sulfonyl)tetrahydro-2H-pyran-4-carboxylic acid trifluoroacetate

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Technology Process of 4-({6-[4-(2,2,2-trifluoroethoxy)phenyl]pyridin-3-yl}sulfonyl)tetrahydro-2H-pyran-4-carboxylic acid trifluoroacetate

There total 1 articles about 4-({6-[4-(2,2,2-trifluoroethoxy)phenyl]pyridin-3-yl}sulfonyl)tetrahydro-2H-pyran-4-carboxylic acid trifluoroacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 701270-59-9
tert-butyl 4-({6-[4-(2,2,2-trifluoroethoxy)phenyl]pyridin-3-yl}sulfonyl)tetrahydro-2H-pyran-4-carboxylate

: 76-05-1
trifluoroacetic acid

: 701270-61-3
4-({6-[4-(2,2,2-trifluoroethoxy)phenyl]pyridin-3-yl}sulfonyl)tetrahydro-2H-pyran-4-carboxylic acid trifluoroacetate

Guidance literature:: In dichloromethane; at 20 ℃; for 4h;

Reference yield: 100.0%

: 6723-30-4
O-2-tetrahydro-2H-pyranhydroxylamine

: 701270-61-3
4-({6-[4-(2,2,2-trifluoroethoxy)phenyl]pyridin-3-yl}sulfonyl)tetrahydro-2H-pyran-4-carboxylic acid trifluoroacetate

: N-(tetrahydro-2H-pyran-2-yloxy)-4-({6-[4-(2,2,2-trifluoroethoxy)phenyl] pyridin-3-yl}sulfonyl)tetrahydro-2H-pyran-4-carboxamide

Guidance literature:: With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In DMF (N,N-dimethyl-formamide); at 20 ℃; for 15h;