2'-Fluoro-biphenyl-4-ylamine hydrochloride

Base Information

Chemical Name:2'-Fluoro-biphenyl-4-ylamine hydrochloride
CAS No.:321-61-9
Molecular Formula:C12H10 F N
Molecular Weight:223.6738432
Hs Code.:
ChEMBL ID:CHEMBL2046996
Nikkaji Number:J1.706.258A
Mol file:321-61-9.mol

Synonyms:321-61-9;2'-FLUORO-BIPHENYL-4-YLAMINE HYDROCHLORIDE;2'-FLUORO-[1,1'-BIPHENYL]-4-AMINE;4-(2-fluorophenyl)aniline;2'-Fluoro[1,1'-biphenyl]-4-amine;2'-Fluoro-biphenyl-4-amine;4-(2'-fluorophenyl)-aniline;SCHEMBL3165600;CHEMBL2046996;KRKXTHCMLYNDRD-UHFFFAOYSA-N;AKOS002683474;2-fluoro-biphenyl-4-ylaminehydrochloride;CS-0450987;F78835

Suppliers and Price of 2'-Fluoro-biphenyl-4-ylamine hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
2'-Fluoro-[1,1'-biphenyl]-4-amine 97%
10g
$ 1290.00

Crysdot
2'-Fluoro-[1,1'-biphenyl]-4-amine 97%
5g
$ 972.00

American Custom Chemicals Corporation
2'-FLUORO-BIPHENYL-4-YLAMINE HYDROCHLORIDE 95.00%
5MG
$ 503.58

Activate Scientific
2'-Fluoro-biphenyl-4-amine 97%
5 g
$ 1133.00

Acrotein
2'-Fluoro-biphenyl-4-amine 97%
1g
$ 275.00

ACHEMBLOCK
2'-Fluoro-biphenyl-4-aminehydrochloride 95%
5G
$ 1020.00

ACHEMBLOCK
2'-Fluoro-biphenyl-4-aminehydrochloride 95%
1G
$ 365.00

Total 12 raw suppliers

Chemical Property of 2'-Fluoro-biphenyl-4-ylamine hydrochloride

Chemical Property:

Boiling Point:301.4±17.0 °C(Predicted)
PKA:4.30±0.10(Predicted)
Density:1.161±0.06 g/cm3(Predicted)
XLogP3:3.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:187.079727485
Heavy Atom Count:14
Complexity:175

Purity/Quality:

98%min ^*data from raw suppliers

2'-Fluoro-[1,1'-biphenyl]-4-amine 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C(=C1)C2=CC=C(C=C2)N)F

Technology Process of 2'-Fluoro-biphenyl-4-ylamine hydrochloride

There total 8 articles about 2'-Fluoro-biphenyl-4-ylamine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 56.0%

: 1993-03-9
o-fluorophenylboronic acid

: 106-40-1
4-bromo-aniline

: 321-61-9
2'-fluoro-[1,1'-biphenyl]-4-amine

Guidance literature:: With dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; potassium carbonate; In 1,4-dioxane; water; at 90 ℃; Inert atmosphere;
DOI:10.1021/acs.jmedchem.0c00512

Reference yield:

: 1993-03-9
o-fluorophenylboronic acid

: 540-37-4
p-aminoiodobenzene

: 321-61-9
2'-fluoro-[1,1'-biphenyl]-4-amine

Guidance literature:: With bis-triphenylphosphine-palladium(II) chloride; sodium carbonate; In 1,4-dioxane; water; Inert atmosphere; Reflux;
DOI:10.1016/j.bmcl.2015.04.038