194785-18-7

Basic information

• Product Name: 6-CARBOXY-X-RHODAMINE
• Synonyms: 6-ROX;6-CARBOXY-X-RHODAMINE;6-CARBOXY-X-RHODAMINE, FOR FLUORESCENCE*;6-CARBOXY-X-RHODAMINE (SINGLE ISOMER);6-carboxy-X-rhodaMine, triethylaMMoniuM salt;6-ROX, 6-CXR;6-ROX [6-Carboxy-X-RhodaMine];1H,5H,11H,15H-Xantheno[2,3,4-ij:5,6,7-i'j']diquinolizin-18-ium,9-(2,5-dicarboxyphenyl)-2,3,6,7,12,13,16,17-octahydro-, inner salt
• CAS NO: 194785-18-7
• Molecular Formula: C₃₃H₃₀N₂O₅
• Molecular Weight: 534.609
• Mol File: 194785-18-7.mol
• Article Data: 9

Chemical Properties

• Appearance: /
• Storage Temp.: −20°C
• Solubility: DMSO: soluble
• CAS DataBase Reference: 6-CARBOXY-X-RHODAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: 6-CARBOXY-X-RHODAMINE(194785-18-7)
• EPA Substance Registry System: 6-CARBOXY-X-RHODAMINE(194785-18-7)

Safety Data

• Hazard Codes: Xi,Xn
• Statements: 36/37/38-48/20/22-40-36/38-22
• Safety Statements: 26-36/37
• WGK Germany: 3
• F: 8
• Hazardous Substances Data: 194785-18-7(Hazardous Substances Data)

Usage

Uses

Different sources of media describe the Uses of 194785-18-7 differently. You can refer to the following data:
1. 6-Carboxy-X-rhodamine is a single isomer, long wavelength rhodamine dye.
2. 6-Carboxy-X-rhodamine is a rhodamine based dye for use in tracer agents, laser dyes, labeling agents for biologics, etc.

InChI:InChI=1/C33H30N2O5/c36-32(37)20-9-10-21(33(38)39)24(17-20)27-25-15-18-5-1-11-34-13-3-7-22(28(18)34)30(25)40-31-23-8-4-14-35-12-2-6-19(29(23)35)16-26(27)31/h9-10,15-17H,1-8,11-14H2,(H-,36,37,38,39)

Upstream product

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Relevant articles and documents

Preparation process of carboxyl-X-rhodamine

The invention provides a preparation process of carboxyl-X-rhodamine, which adopts 8-hydroxyjulolidine phenol and trimellitic anhydride as raw materials, an intermediate 5, 6-carboxyl-X-rhodamine is synthesized by a direct cyclization method, a high-boiling-point solvent is adopted as a cyclization medium, and a cyclization product has poor solubility in the solvent and can be precipitated in a reaction system, so that the yield of 5, 6-carboxyl-X-rhodamine is increased, and the yield of 5, 6-carboxyl-X-rhodamine is increased. Therefore, the reaction conversion rate and the purification simplicity are obviously improved; 5, 6-carboxyl-X-rhodamine and organic amine are salified, so that the separation cost is greatly reduced, the operation steps are simplified, and the industrial production of carboxyl-X-rhodamine becomes possible; an acid precipitation method is adopted, the 5-carboxyl-X-rhodamine ammonium salt and the 6-carboxyl-X-rhodamine ammonium salt are converted into the 5-carboxyl-X-rhodamine and the 6-carboxyl-X-rhodamine, and the efficiency is high; the whole preparation process has the advantages of simplicity and convenience in operation, low equipment requirement, low cost, high equipment use efficiency and the like, and meets the requirements of industrial production and application.

CELL-PENETRATING FLUORESCENT DYES WITH SECONDARY ALCOHOL FUNCTIONALITIES

The invention relates to novel cell-penetrating fluorescent dyes with with secondary alcohol functionalities having one of the following general formulae I-III and 4: The invention also relates to the use of these compounds for optical microscopy and imaging techniques.

METHODS FOR SYNTHESIZING RHODAMINE DYES

Described herein are methods for the regioselective synthesis of substituted rhodamine dyes.